Posted by Cloud 9 on December 10, 2001, at 5:51:55
In reply to Effexor an opiate?, posted by dhldn on December 8, 2001, at 11:40:37
>Venlafaxine, when used in larger doses of over ~150 mg, may cause hypertension in some people, another problem that requires monitoring and may debar its use in some patients.
>What the place of venlafaxine should be at lower doses (ie up to ~150 mg) in primary care is hard to judge. It shares the low interaction propensity (via CYP450) of sertraline and citalopram; but at lower doses probably has no particular advantages and is much more toxic in over-dose than any of the SSRIs or even than some of the old tricyclic antidepressants.
Just a few questions regarding your entry...
Does this mean at a low dosage it is inferior OR equal to other SSRI's in efficacy? If it's a potentially toxic drug is it possible to over-dose at such a low dosage? What are the advantages of taking effexor at high doses ( >150mg)? Would you recommend another SSRI in lieu of Effexor for GAD?
Thanks for your help.
poster:Cloud 9
thread:13781
URL: http://www.dr-bob.org/babble/20011202/msgs/86434.html