Posted by PaulB on December 2, 2001, at 23:26:28
In reply to Re: SSRIs and MAOIs for SP » PaulB, posted by Elizabeth on December 2, 2001, at 17:04:00
I sense that we are getting our wires crossed on certain issues but its been an interesting discussion. I cut the previous stuff because I wanted to open up a new discussion but still continues on the theme of MAOIS vs SSRI's
First of all I would agree that Moclobemide does not hold a good rep as being a powerful antidepressant. You really seem to know your stuff so I would like your opinion on my current drug-line up.
Sertraline 200mg/day
SAM-E 200mg/day/empty stomach
Lorazepam-PRN and when Sertraline 'poops-out' I come off Sertraline, load on 5-HTP and use Lorazepam until the Sertraline 'kicks-in' again.What do you think of this combination for serious social phobia, serious depression/anger, moderate obsessive compulsive disorder and generalised anxiety disorder?
This may not always be my combination therapy because there is clear evidence that the MAOI's are better for social phobia(my biggy)than the SSRI's. The problem is that the MAOI's are not selective and I believe that is a disadvantage. From your previous posts I sense you may not agree. Have you heard of augmeting Nardil; perhaps with an atypical antipsychotic or a 5-HT3 antagonist which were being investigated for social phobia a short while ago. The problem is that the MAOI's interact with many drugs so polypharmacy with them could be dangerous and potentially lethal. But what a weapon against social phobia a selective MAOI would be, dont you think?
poster:PaulB
thread:85575
URL: http://www.dr-bob.org/babble/20011202/msgs/85839.html