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Re: mirapex for anhedonia/apathy - question » Jenna S.

Posted by ChrisK on December 2, 2001, at 3:46:10

In reply to Re: mirapex for anhedonia/apathy - question, posted by Jenna S. on December 1, 2001, at 18:39:35

I asked my pdoc about Mirapex a few weeks ago and he wasn't too keen. But I'm not going to give up that easily! So I was wondering if you would let me know which studies convinced your pdoc to let you try Mirapex?
>
> Jenna

Jenna, go to www.google.com and do a search on MIRAPEX and DEPRESSION. There are plenty of articles but start with these two:

http://www.parkinson.org/mxdepress.htm

http://www.psycom.net/depression.central.resistant.html

The second one you need to look about half way down the page. Both studies show good results. Personally I think that the theraputic dosage for depression augmentation is more in the range of 3-6 mg/day. The one study tried a dose of 5 mg/day but didn't get good data at that level because (I read somewhere else) too many people had problems with nausea at the higher level.

Good luck with your doctor. Mine used to get a kick out of the homework I did on my treatment. I almost always brought in a pile of papers to suggeest something different that might work. Now I feel much better and I think he misses the monthly updates and studies I would bring in.

Chris


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