Posted by SLS on November 20, 2001, at 15:24:46
In reply to Re: amphetamine sensitization article, posted by JGalt on November 19, 2001, at 15:51:14
Hi.
> I've read on this board ppl saying that Prozac+adderal doesn't poop out much...and this mazindol might even be a better idea. What do you think?I have been interested in mazindol for quite some time. I believe it was initially investigated as an antidepressant. An anologue, ciclazindol, was also being developed as an antidepressant (by Wyeth, I think), but was dropped - probably for lack of efficacy.
Mazindol is a very selective ligand for the dopamine uptake transporter and is often used in assays. However, I am not sure if it actually inhibits the reuptake of dopamine.
Does anyone know?
If it is, it might be interesting to see if it has utility as an adjunct to antidepressants or to low-dosage neuroleptic strategies.
- Scott
poster:SLS
thread:84550
URL: http://www.dr-bob.org/babble/20011113/msgs/84782.html