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Re: lamictal titr-side effects..son had them; John

Posted by Karen Curtis on November 17, 2001, at 13:54:07

In reply to Re: lamictal titration -side effects..son had them » Karen Curtis, posted by JohnX2 on November 16, 2001, at 14:36:58

Yes, John, our pdoc was aware of it (he is excellent), and prescribed it at 12.5 for 2 weeks, hen 25mg for 2 weeks, then 50 for two weeks, and when we got up to 62.5 is when my son got sick. However, he had a little infection around his ring finger tip, and I am now convinced it is also from the lamictal Never again will we try this med! My son is still sick- he started with a fever, then got mouth sores (painful canker sores) all in his mouth, and thrush on his tongue. He still cannot eat much at all, too painfull. So now he is still on lithium and depakote too. We wanted to replace the lithium with the lamictal. (Hey, keep it in the L's). Well, we have to stick with the lithium for now- it just wasn't doing as much as we hoped to make the side effects worth it, (so now we give it all at night) but with the addition of the seroquel along with my sons geodon, he has improved. So maybe this combo will work for awhile. Karen Curtis


> was your pdoc aware of the interaction
> between depakote and lamictal? (depakote
> increases lamictal in the body). Do you
> think this was the primary culprit in the
> adverse reaction?
>
> -john
>
>
>
> > > Hello,
> > >
> > > Three questions:
> > >
> > > --Just wondering if anyone knows the liklihood of developing the rash/dangerous side effets, after stabilizing at a particular dose?
> > >
> > > I titrated somewhat aggressively, but cautiously, and am currently at 150mg/day (75mg twice a day). This was my second day at 150mg. Haven't had any side effects to speak of to this point. Think I'm getting some benefit at this level, and plan to stay at this dosage for at least a week or two, and see how it goes. (fwiw, also taking 400mg wellbutrin sr)
> > >
> > > Also, wondering:
> > >
> > > --what dosage people have found to be an effective/theraputic/maintenance dose?
> > >
> > > --are those of you who are NOT taking this specifically for Bipolar (i.e.: are using it primarily for antidepressant effects), typically using it to augment another AD, or trying it as monotherapy?
> > >
> > > Thanks for any info/feedback/insights/personal experiences.
> > >
> > > michael
> >
> > my son was on lamictal and depakote, and we titrated the lamictal so very slowly, and my son STILL got thrush on his tongue, and mouth sores all over, hasn't been able to eat for a week, we ended up in the ER. The pdoc said it was the start of SJ syndrome! Scary, but I bet if he was not on the depakote, he would not have had the problem. Karen Curtis


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