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Re: Adderall --

Posted by Mitch on October 3, 2001, at 0:08:00

In reply to Re: Adderall --, posted by gardengal on October 2, 2001, at 23:19:21

> > > >
> > > > The doctor also told him that he would crash big time every few days.
> > > >
> > >
> > > Just a note -- I recently tried Adderall, and wasn't warned about this "crashing" effect. But in my case, your friend's doctor was right! I felt great for about 4 or 5 days, then crashed HARD. Felt like @#$%#. I tried it again, felt good for about 3 days, then crashed again. It sucked. I guess this doesn't happen to most people, but according to some smart people on this board, it is pretty common.
> > > -cindy
> >
> >
> > This may be far fetched.
> >
> > AndrewB has reported that memantine, an experimental drug, has enabled him to continue to respond to Adderall when he had previously experienced poop-out after 3 days.
> >
> > Memantine is currently in phase III trials (just one step short of approval) for treating Alzheimer's Dementia. Andrew feels that memantine might prevent poop-out by blocking a specific glutamate receptor known as the NMDA receptor. It reduces glutamate stimulation.
> >
> > Lamictal (lamotrigine) also reduces glutamate stimulation, but in a different way. I'm wondering if Lamictal can help prevent amphetamine poop-out.
> >
> > It's just a thought.
> >
> >
> > - Scott

Thanks for that info, Alzheimer's demnentia, huh? Lamictal is a last try (because of the rash) on my pdoc's list. Perhaps memantine would be more of a mood stabilizer rather than an antidepressant?

As far as Adderall goes-it proved to be one of the best mood *stabilizing* agents I have ever taken. I felt a *mild* euphoria and insomnia for about three or four days which yielded to a quite euthymic mood with consistent sleep/wake cycles and circadian rhythyms. I just had trouble with the anxiety it provoked due to being newly hyperaware of non-verbal social communications.


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