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Re: Augmenting Effexor with Wellbutrin: a reprise

Posted by galtin on September 22, 2001, at 14:19:26

In reply to Augmenting Effexor with Wellbutrin: a reprise, posted by pellmell on September 14, 2001, at 20:46:47

> Hello all,
>
> I know this has been discussed before, but I'm not in the mood for something from PB's freezer: I want some fresh advice.
>
> So yeah, Effexor is working for me, but not as well as I'd like. I saw my pdoc this week, but for reasons you can imagine wasn't in the mood to whine about myself too loudly. He recommended playing with my dose to see whether 150mg or 225 is better in terms of efficacy vs. side-effects, and if I didn't want to do that he'd try me back on Prozac or one of the other two SSRIs I haven't tried (Paxil and Celexa).
>
> I've decided to take matters into my own hands. Maybe in the future I'll test his imagination, but I didn't have the heart this week. Anyway, I have a bottle of sixty 150mg tablets of Wellbutrin SR from a failed trial at the beginning of the summer. I'm thinking with the calm that Effexor brings me I'll be able to handle it this this time, and with the bleh that Effexor brings too the activating effects of Wellbutrin will be helpful.
>
> I guess I'm asking, then, for other peoples' experiences with this combo, and advice on how to mix it (ie, what time of the day should I take the Wellbutrin, etc.). Today was my first day trying this, and I took the Effexor XR last night (it tends to make me sleepy) and the Wellbutrin at noon today.
>
> Thanks in advance. Oh, any other augmentation suggestions that you think I should bring up with my pdoc are welcome, too.
>
> -pm

Pellmell,

When my doctor augmented Effexor with Wellbutrin it produced positive results. Also, don't rule out Effexor based on too low a dose. I had to get to 225. My depressions are noreprinephrine related and Effexor does not address this until the daily dosage surpasses 150mg. An increase in dosage lowered rather than raised the severity of the side-effects.

Good Luck,

galtin


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