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Re: MAO Midday Slump? Thank-you all nm » Lorraine

Posted by kregpark@yahoo.com on September 9, 2001, at 4:42:38

In reply to Re: MAO Midday Slump? Thank-you all nm, posted by Lorraine on September 3, 2001, at 21:54:29

Hi,
I took Nardil 90mg 2 years several years back
for severe SP, and I experienced exactly the same
thing.

At the time I took lots of caffiene drinks.
Helped but problem still there for awhile.
Gormans' "Essential Guide to Psychiatric Drugs"
v3, 1997, paperback, small, $8, mentions this
about Nardil, and that timing of dosing makes
little difference, it tends to happen around 2-3
if it happens.

I now take 60 Nardil, 2.5 Klonopin, 75 Provigil.

Amazingly I discovered something new yesterday.

Neostigmine reversed some (what I thing wass
anticholinergic sedation) when I was out late,
tired and took 7mg more Nardil, about 10mg
Wellbutrin, and 25mg Provigil, but felt lousy
and unsocial. Was late and I was going to head out
when I decided to try a 7.5 neostigmine just
for the heck of it.

(I usually don't tinker around anymore like
above as it doesn't usually pay for me, I did,
but was *amazed* how quickly I turned around
on the 7.5 (very little) neostigmine.

I was alert and happy again, hung around till 1am
and left. Driving home suddenly I was feeling
something like either hypomanic (a first I believe)
or else a lift of some sort of dysthmia beyond
what I though I had) I felt so good I couldn't
believe it, alert, not stoned, happy as hell,
(it was a great week for me though) - etc.

Neostigmine last a few hours.
2 years ago I wanted to try the new cholinergic
called Aricept (donepezil). BTW bethanechol
might also help like neostigmine in afternoon.

Aricept has long duration and is getting press now.
I noticed it often can cause mania.

I'm not surpirsed and wonder if I had a bit
of hypomania going.

In any case, just wanted to throw it out.

kregpark

http://www.socialfear.com/

> > Hi.
> >
> >
> > > Does anyone have any thoughts about the MAO midday slump?
> >
> > Well, if you experience this within an after eating, it might be an exaggeration of the normal sleepiness that many people experience. Parasympathetic stuff I guess.
> >
> > Also, I think hours between 1:00 and 3:00 are normal "down-times". This is probably the impetus for the traditional siesta of the Spanish. I find 2:00 the absolute worst.
> >
> > Your guess regarding low-blood pressure is a good one. While I was on Parnate, one of my doctors suggested that blood-pressure ebbs at about 4:00. I found this to be true. His suggestion was to drink a cup of coffee at this time. I found that it worked well.
> >
> > That's about all I can think of.
> >
> >
> > - Scott


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poster:kregpark@yahoo.com thread:76827
URL: http://www.dr-bob.org/babble/20010907/msgs/78343.html