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Re: Does Amisulpride help with depression, anxiety?

Posted by JohnL on September 1, 2001, at 5:43:04

In reply to Does Amisulpride help with depression, anxiety?, posted by Margit on August 31, 2001, at 20:01:37

> I was wondering if Amisulpride helps with the above? Zyprexa which I am currently on seems to do that. My problem with it though is sedation and acid reflux. So, I thought I give Amisulpride a try and have better luck in regard to side efeects. But I would like it to help for depression and anxiety. Anybody know.
> Thanks for any responses.
> Margit

Hi Margit,
Amisulpride is absolutely wonderful for the symptoms you described. I have tried them all, and Amisulpride was my favorite. I am currently on Zyprexa, which is my second favorite of the bunch. I switched merely because Amisulpride did not help me with sleep. I needed help with sleep. Zyprexa is great for my sleep. The two drugs seem to work fairly similar, though I must admit Amisulpride was better.

Clinical studies look promising with Amisulpride. It is at least as good, and often better, than antidepressants.

It was a while ago, but one of the regular psychobabblers recorded and studied the results of other psychobabblers who had tried Amisulpride. I don't remember the exact numbers, but it was something like 70% experienced significant improvement. Though those numbers are similar to what can be expected from any drug, the real interesting and encouraging part is that ALL the people who tried Amisulpride were very difficult treatment resistant patients. For one drug to help 70% of the people in a very difficult population is quite amazing, as I see it.

I still take Amisulpride from time to time. Here's why. My current cocktail of Prozac+Adrafinil+Zyprexa does a wonderful job. But, every now and then I experience a sinking spell. When that happens, I take one dose of Amisulpride. It lifts me right back up in about three hours, and then I am fine for weeks.

Amisulpride can work quickly, or it may come on slowly over a period of weeks. But I just wanted to say that if you have responded well to Zyprexa, then you could likely respond well to Amisulpride as well. I respond well to either one. Amisulpride is more stimulative at low doses (25mg to 75mg). Ironically, you could possibly experience increased anxiety at first, which will later disappear on its own. I think the greatest benefit I ever noticed from Amisulpride was the calm and cool relaxed feeling I had in anxious situations. But that didn't happen overnight. It took a few weeks.

Hope this helps.
John


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poster:JohnL thread:77159
URL: http://www.dr-bob.org/babble/20010828/msgs/77236.html