Posted by Elizabeth on August 10, 2001, at 15:19:37
In reply to Re: I may need help...., posted by medlib on August 9, 2001, at 12:13:43
> I'm no brainiac, but grapefruit juice with low dose selegiline seems worth trying, since it is known to inhibit metabolism of substances from caffeine to felodine to verapamil.
Grapefruit juice contains a CYP3A4 inhibitor. I don't think that it would make much of a difference with selegiline.
> If, with that mechanism, you can decrease your dosage of selegiline to 10mg/day, you can eventually restore its selectivity for MAO B.
Not if the serum concentrations remained the same (as would be the case in a poor metaboliser).
-elizabeth
poster:Elizabeth
thread:69963
URL: http://www.dr-bob.org/babble/20010809/msgs/74500.html