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Re: Gabapentin/gabitril » MM

Posted by Mitch on July 31, 2001, at 1:47:14

In reply to Re: Gabapentin » SalArmy4me, posted by MM on July 31, 2001, at 0:04:45

> Thanks again. Someone on another board favors gabatril over gababentin because it makes them feel less spacey or stoned. I wouldn't mind that much I don't think (I'm extremely spacey anyway) but weight gain is a concern for me. They said gabatril was exactly like gababentin, except without side effects, so I guess I assumed it doesn't have weight gain. I value your opinion though and will take it to heart. Thanks.

MM,

Been on both (not at the same time) gabapentin (Neurontin) and tiagabine (Gabitril) pushed to fairly high doses (1800mg/Neurontin/day), (24mg/Gabitril/day). I had cognitive problems with Neurontin only above 900mg/day, but had cognitive trouble with the Gabitril just about from the getgo-although I did notice a definite antidepressant effect with the Gabitril (but also noticed a definite AD effect with Neurontin). I was seeing a neuro when I was on them and he pushed for rapid dose escalation in both cases-so that may have contributed. The nice thing about Gabitril (as opposed to Neurontin) is that you *might* get away with once or twice daily dosing. Perhaps if the Gabitril was carefully and slowly increased (like Topamax needs to be) then some of the cognitive side-effects from the Gabitril could be avoided or at least lessened. In my opinion I think the Gabitril could be more effective for chronic pain syndromes than Neurontin (if tolerated otherwise). I experienced a definite "anesthesia" of sorts at the highest dose (just before discontinuing).

Mitch


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poster:Mitch thread:72632
URL: http://www.dr-bob.org/babble/20010725/msgs/72679.html