Posted by Mitch on July 23, 2001, at 10:18:45
In reply to Re: Klonopin and it's Risks - Myra, posted by Joe Schmoe on July 22, 2001, at 23:16:54
Joe, How much Wellbutrin are you taking? I also take Klonopin for SP and when I was taking Wellbutrin with it I only took 25mg twice-three times a day and work up very slowly (I was quartering 100mg SR tabs). You may be titrating the dose upwards too quick or got started out with too high a dose. I found that just 75-150mg total in a day was plenty (divided up). I also think it worked better (from what I can remember) by splitting up my Klonopin with it. I think I was taking 25mg WB+.5mg Klonopin with each WB dose. The WB peaks fast and is quite buzzy, and the Klonopin works best the first few hours after you take it because you are getting the "parent" drug first-then it metabolizes in your body I think into desmethyl-clonazepam which is active, but not as active as the parent. Interestingly, the WB has active metabolites as well (with longer half-lives)which may explain your insomnia. I would suggest taking Klonopin together with the WB and don't take any WB later than say 4-6pm (to help with the insomnia).
Mitch
> Is this true? I mean is this anecdotal or is this supported by studies? Since Klonopin only seems to last (for me) for about six hours in terms of social phobia protection, I would find it hard to believe taking it once a day is optimal. Also taking this large a dose at once I would think would really dope me out.
>
> I am new to Klonopin and trying to fumble my way toward discovering an effective dosage for me. Since I am also starting Wellbutrin (third week) this has been a challenge. I see my doc this week, wondering what to tell her. My dosage now is 1.5 mg a day, which I take 1 mg in the morning and .5 mg around 2 PM, although tonight for some reason I had to take an extra .5 in the evening - maybe the Wellbutrin is starting to kick in and make me more anxious. It is all so confusing. I think I will ask for more Clonopin when I see her.
poster:Mitch
thread:55769
URL: http://www.dr-bob.org/babble/20010720/msgs/71494.html