Posted by Elizabeth on June 15, 2001, at 21:56:26
In reply to serotonin syndrome, posted by krista on June 15, 2001, at 16:44:12
Luvox and Serzone have the potential to decrease each other's metabolism, so that you end up having elevated levels of both drugs in you. "Serotonin syndrome" is a loose description for a lot different severe adverse reactions involving serotonergic drugs (usually two or more in combination: it was first identified when somebody tried combining MAOIs and Prozac). It often resembles neuroleptic malignant syndrome, an adverse reaction that occasionally occurs on antipsychotic drugs.
The symptoms can vary a lot, but the most common ones are: excessive sweating; high, low, or labile blood pressure; rapid pulse; dilated pupils; nausea and vomiting; muscular rigidity (e.g., jaw clenched shut); twitching (myoclonus); exaggerated reflexes; shaking or shivering; chattering teeth; incoordination; fever; mania or hypomania; agitation; delirium; and seizures.
I hope this isn't what you have; it's a serious medical emergency and is sometimes fatal. Sometimes SSRIs can cause some agitation when you first start taking them, and that might be all it is. Regardless, I would suggest, at a minimum, that you get in touch with your doctor as soon as possible, since this drug combination seems to be very bad for you. Also, I strongly suggest that you not take any more Luvox until you are able to get in touch with your doctor.
-elizabeth
poster:Elizabeth
thread:66590
URL: http://www.dr-bob.org/babble/20010612/msgs/66624.html