Posted by Mitch on June 13, 2001, at 12:22:13
In reply to Re: Paxil for melancholia, posted by ben on June 13, 2001, at 3:58:10
> > > Does anyone have good experiences with paxil for melancholic depression (low mood) ?
> >
> > I might be confused about what you're saying, but "melancholia" actually defines a specific symptom cluster; it doesn't mean sad or low mood. SSRIs may be less effective for this subtype of depression than tricyclics (although the evidence is inconclusive). Remeron and Effexor are supposed to be effective, and MAO inhibitors probably are also although they have been studied less in this condition. I'm not sure about Edronax, but I'd give it more of a chance.
> >
> > If you had partial responses to other medications, perhaps combination therapy would be the way to go? I also note that some of the doses you listed seemed a bit odd. 100 mg of Celexa is pretty high while 75 mg of Zoloft is kind of low. 150 mg of Effexor is a decent dose but many people need before, and Effexor does generally work better the more you raise the dose (unlike SSRIs, which generally plateau at a certain dose).
> >
> > The side effects you mentioned should get milder with time, BTW.
> >
> > -elizabeth
>
> thanks for your reply elizabeth
> 100 mg Celexa was true, 75 mg of Zoloft was too much because of persisiting nausea, 150 Effexor was too much for my head (2 month with headache). For me melancholia means very low mood (all the time crying); but your definition is the right one. I had combinations with these drugs and others (antipsychotics) and never reached stability in my mood. I failed of Lithium cause of awful nausea (in combo with 100 mg Celexa !!!). Remeron at 7.5 mg was too sedating and i felt stoned.
> benBen, I think Elizabeth is right about the tricyclics. I have a very touchy gut and get nauseated really easily with the meds you just listed. Maybe nortriptyline or desipramine (something not too sedative)? Plus AD's that work on norepinephrine/dopamine might be better for your "melancholia". Have you tried any Wellbutrin?
Mitch
poster:Mitch
thread:66228
URL: http://www.dr-bob.org/babble/20010612/msgs/66324.html