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Re: Tired of chronic BP II misery loosmrbls

Posted by Mitch on May 30, 2001, at 1:58:54

In reply to Tired of chronic BP II misery, posted by loosmrbls on May 29, 2001, at 12:50:44

> I simply am sick to death of all these different drugs, I truly think there will never be a good day again.
> After a hospitalization from mid-April to early May for depression, I was sent home on Depakote and Zoloft. My pdoc quit the Zoloft after I told him it didn't seem to add any effect to the Depakote except give me a headache. Within two weeks, I was depressed again. Not as bad (no hospital needed) and a more withdrawn, dark, flat depression. I guess the Depakote was stopping severe swings and the anxiety.
> As I mentioned in an earlier post, I quit all my meds and felt much better. For a few days. Then the depression came back, and the mood instability, and everything else.
> A week ago, was re-started on Depakote and started on Remeron. Even with this AD, I am an irritable, short-tempered prick. I get mad/frustrated so easily, look for arguements (mostly with wife), and can't stand it. I've had this response with every AD. So it's not a switch into mania, I'd say. I mean, what are the chances of EVERY AD causing this reaction within 1-2 days of starting medication. Especially with stabilizer on board? Is it an "unmasking" of depressive irritability/anxiety? Or something else?
> Any ideas? I can't stand it, neither can my wife. My doctor seems VERY hesitant to use any neuroleptics. I do have some suspiciousness/paranoia, but no delusions ro psychosis to speak of.
> I feel a hospital trip may be in order soon if things don't calm down soon.

This is really weird, but I found even Remeron caused me to be bitchy too! (BP-II, as well-supersensitve to antidepressants-with ADHD). Even Buspar at 10mg/day caused me to get nearly physically violent.
Hey, this is a REAL long shot, but what about asking for some LOW-dose Dexedrine or Adderall to see what that does (NOT while you are taking ANY AD). Yor pdoc would probably freak, but I have taken it in the past (Adderall) and my cycling STOPPED! It *just might* work with the Depakote-who knows? If you are bitchy, picking fights, can't focus, getting frustrated-sounds a lot like ADHD as well. ..OR..
Also-I can't hack more than just tiny doses of AD's-but they do help. I am talking 2.5mg of Prozac for example. Maybe he can restart you on the Zoloft at just 12.5mg/day and let that go for a couple of weeks-see how you feel.





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