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Re: Parnate and pain killers » Caty

Posted by Elizabeth on May 17, 2001, at 14:55:57

In reply to Parnate and pain killers, posted by Caty on May 15, 2001, at 14:23:56

> I'm trying to find a pain killer
> I can take. My doctor gave me Vicodin, which does
> nothing for me. Every drug that I check says it should
> not be taken with an MAOI. I have checked things in
> the the Darvocet family and the Percocet family. Are
> these warnings valid, or are they trying to cover all
> bases? Any suggestions/experiences would be greatly
> appreciated. Thanks...

They're trying to cover all bases (especially the ones on their *sses < g >).

Oxycodone, which is a step up from hydrocodone among the opioid ("narcotic") pain killers, is safe to take with MAOIs (as is hydrocodone). (Percocet is oxycodone with Tylenol; Vicodin is hydrocodone with Tylenol.)

The only opioid PKs that I can think of that are definitely unsafe are Ultram and Demerol. (Morphine is considered the preferred PK to use as a substitute for Demerol in patients on MAOIs.)There have been a couple of published incidents involving propoxyphene (Darvon) with MAOIs, as Sal notes. Darvon is very weak, though, and if Vicodin didn't work then Darvon probably won't either.

Hope this helps. Please don't hesitate to ask about specific PKs that you're considering.

-elizabeth


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