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Re: Methadone, Propoxyphene and APAP

Posted by dougb on May 14, 2001, at 17:33:28

In reply to Re: Methadone DianeD, posted by Elizabeth on May 10, 2001, at 7:10:13

> (Personally, I have tried a number of different opioids and found all of them to be activating. But that's *just me*.
---i also find them to be activating, maybe this has something to do with the subset of depressives who are helped by the opiates.
> Vicodin seems like a poor choice to me since it contains acetaminophen ("APAP" -- i.e., Tylenol) as well as hydrocodone.... you may need ever-increasing doses, in which case a combination product such as Vicodin is an absolute no-no.
---Vicoprofen is Vicoden without the APAP
---Darvon-N (propoxyphene) has not additives. Is an alternative you may with to explore, chemically related to Methadone, it has the following things in it's favor:
- At the lower dosage it has a rather flat delivery curve so it feels like less of a 'rollercoaster' than Hydroc.
- Over a period of days, the metabolite builds up in the system, so give it 3-4 days before you give up on it
- I find myself frequently going 6 hours between dosses instead of 3-4 in Hydroc.




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