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Re: Seratonin Syndrome » mytwogrlsmom

Posted by Sunnely on May 11, 2001, at 23:59:46

In reply to Seratonin Syndrome, posted by mytwogrlsmom on May 11, 2001, at 22:59:21

Hi Mytwogrlsmom,

The combination of fluoxetine (Prozac) and phentermine (Ionamin, Fastin) can lead to a potentially serious (sometimes fatal) condition called "serotonin syndrome." This condition usually results from the combination of drugs that enhance release of serotonin in the brain. There have been anecdotal reports of serotonin syndrome developing from this combination.

FYI, phentermine was one of the weight loss drugs of the once popular combination "phen-fen" ("phen" for phentermine and "fen" for fenfluramine). With the findings of heart valves problems developing from the use of fenfluramine or Pondimin and dexfenfluramine or Redux, these drugs were voluntary removed from the market. With the loss of the "fen" partner, some entrepreneurs suggested to combine "phen" with Prozac and called it "phen-pro." Eli Lilly, the manufacturer of Prozac, did not approve or endorse the use of Prozac with these combination drugs for weight loss. However, with Lilly's patent for Prozac set to expire at the end of August 2001, and generic fluoxetine then becoming available, this suggested combination may surface again. Perhaps being called "phen-fluo"?

Are you taking both drugs to lose weight or taking Prozac as an antidepressant and phentermine for weight loss? You should really discuss this drug combination with your prescriber.

++++++++++++++++++++++++++++++++++++

> I am taking 60mg of Prozac and 3.75mg of Phentermine. Someone told me this could cause a problem. Can anyone tell me more? Thank you, Renee


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poster:Sunnely thread:62569
URL: http://www.dr-bob.org/babble/20010507/msgs/62580.html