Posted by SalArmy4me on May 5, 2001, at 23:06:45
In reply to Serzone Sedation, posted by afatchic on May 5, 2001, at 18:31:15
I postulate that nefazodone can be taken all at bedtime, due to the fact that its Triazole-dione metabolite has a half-life of 18 hours, and the the mean half-life of total label ranged between 11 and 24 hours. Taking it all at bedtime would minimize daytime sedation.
> Hello All, This is my first post in many months. I suffer from dysthimia (a chronic form of depression) and have been on ADs since 1989. Most of the time, I took Prozac and Trazodone, which are a wonderful combination for me except for the sexual side effects. I tried augmenting with Buspar for a few weeks and had zero results. Now I'm on Serzone. I've been taking it for about a month. I started at 75mg twice a day and am now up to 150mg twice daily. I barely have the energy to work and have started sleeping through my alarm and being late to work. I'm normally very punctual. Anyone have any advice? I've asked my doctor to reduce my dose and let me gradually increase the dose. So far she hasn't responded to my message (and no, I'm not one of those annoying patients who monopolizes a doc's time). Should I be considering augmenting with something more activating? Thanks for your responses