Posted by stjames on April 22, 2001, at 22:32:30
In reply to Longterm safety of SSRI's and other psych. drugs, posted by Ryan on April 22, 2001, at 21:56:01
> I have social phobia, major depression, and ocd. I've used Effexor XR, Zoloft, Gabitril, Klonopin, Adderall, Paxil, Buspar and Celexa.
> Effexor worked best and controlled more symptoms than anything else. I used 300mg. per day. My problem is that I am afraid to take any medication anymore. I read a study that stated that Prozac, Zoloft, Pondimin, and Meridia change the shape of seretonin receptors in the brains of rats after only 14 days of administration of extremely high doses. It isn't known if these changes are permanent or harmful. I'm angry that this study wasn't done BEFORE the drugs were released. I thought these studies were done before the drugs are cleared by the FDA. I'm now scared of taking ANYTHING because of this. If anyone knows of other research on this subject or other ways of treating my problems PLEASE post.James here....
How do you know these changes are harmful ? Why do you think they are ? Something has to change if a drug is to be effective. The changes you mention are at least 50 years from us understanding what they really mean. Do we follow
Chicken Littles logic, be scared of everything we don not understand. So we don't give people these drugs because of something that happens that we will not understand for 100 years. Even though people have been taking AD's for 50 yrs we pull them due to something happening at the micron level. We allow more people to suffer and die due to mental illness, no because of big issues like toxisity and mutations but worry to death about sometyhing at the micron level. STUPID.Please find something else to worry about. Running out of matter in this system/univiverce
or the balance of matter to expansion changing so
a big big bang or implosion and w are all gone has far more info on it than changes to seretonin receptors. Look up the "Theory of everything"When you can answer these questions you can start worring about seretonin receptors.
1) What do the they look like
2) What do they do
3 What does their structure look like through out their life
4) How does structure relate to function
5) Account for being able to function normaly with 90% loss of seretonin receptorsJames who is very tired of this thread coming up again. Worry about what you know and can prove. Don't worry about little facts that we are 50-100
yrs from beginning to understand. I also do not understand why you an angry, all kind of tests were done, tests where we understand what the results mean. Tests that give results that we are no where close the understaning proves nothing. There is no point is being afraid fo what we don't understand.James
poster:stjames
thread:1356
URL: http://www.dr-bob.org/babble/20010417/msgs/60813.html