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Re: Depression, Antidepressants, Life (ramble)

Posted by Cam W. on April 18, 2001, at 11:57:01

In reply to Re: Depression, Antidepressants, Life (ramble) » SLS, posted by Cam W. on April 18, 2001, at 11:45:48

The placebo effect and relaxation response: neural processes and their coupling to constitutive nitric oxide George B. Stefano, Gregory L. Fricchione, Brian T. Slingsby & Herbert Benson Brain Research Reviews, 2001, 35:1:1-19
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The placebo effect and relaxation response: neural processes and their coupling to constitutive nitric
oxide George B. Stefano a,b A gstefano@li.net, Gregory L. Fricchione a,c,d , Brian T.Slingsby b and Herbert Benson a
[a]The Mind/Body Medical Institute, CareGroup, Department of Medicine, Bet Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115,USA
[b]Neuroscience Research Institute, State University of New York at Old Westbury, Old Westbury, NY 11568, USA
[c]The Carter Center Mental Health Program, 1 Copenhill, 453 Freedom Parkway, Atlanta,GA 30307, USA
[d]Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical Center, 75 Francis Street, Boston, MA 02115, USA.
A Corresponding author. Neuroscience Research Institute, State University of New York at Old Westbury, Old Westbury, NY 11568, USA. Tel.:
+1-516-876-2732; fax: +1-516-876-2727
Manuscript accepted 17 October 2000;

Abstract

The placebo effect appears to be a real phenomenon as is the scientifically demonstrated and examined relaxation response. Given this, we attempt to understand how these phenomena work in light of our current understanding of central and peripheral nervous system mechanisms. Central to our hypothesis is the significance of norepinephrine, nitric oxide and opioid signaling both in the central and peripheral nervous system. In this
regard, we find that nitric oxide controls norepinephrine processes on many levels, including synthesis, release and actions. In closing, we conclude that enough scientific information exists to support these phenomena as actual physical processes that can be harnessed to provide better patient care.
© 2001 Elsevier Science B.V. All rights reserved.
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poster:Cam W. thread:60209
URL: http://www.dr-bob.org/babble/20010417/msgs/60319.html