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Richelson-GABA antagonists

Posted by PaulB on April 12, 2001, at 17:56:16

Because the benzodiazepines are unselective for GABA receptors and stimulate gabergic receptors involved in reducing anxiety and panic as well as those receptors involved in sedation I was wondering whether benzodiazepines could be augmented with selective GABA antagonists to allow a person to continue to experience the anxiolytic effect of the drug but eliminate the amnesic and sedative effects that the benzodiazepines have? Can you mention any that are available?


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poster:PaulB thread:59594
URL: http://www.dr-bob.org/babble/20010411/msgs/59594.html