Posted by Daveman on March 29, 2001, at 21:29:51
In reply to Table: Side effects of different Antidepressants, posted by jb on March 28, 2001, at 10:11:32
Thanks, jb, for the link- it was a very interesting article. One thing I noticed is that Celexa is not indicated as causing insomnia (as opposed to Prozac and Zoloft among the SSRI's), in fact it is indicated as causing sedation. Well, then, is it just in my mind (pardon the choice of words) that I'm still having difficulty sleeping? (I'm on Celexa 40 mg. per day.)
Also, Celexa is indicated as having fewer drug interactions than other SSRI's. Does this mean that Celexa is safer to take with a benzo (say Xanax or klonopin) than other SSRI's?
Finally, the article advises a nine-month continuation after full remission of depressive symptoms, which is precisely what my pdoc has advised. Then the article says that responses to AD's are questionable anyway due to a 30 percent placebo response. How would I know if I'm embarking on a long-term treatment based on a placebo response? It seems unlikely, or I would have responded to the Paxil which was tried first , but it's a thought anyway.
Thanks again for the link.
Dave
> I discovered a very informative article which includes a table indicating the side effects of many Antidepressants, including, in many cases, the pharmacological reasons for the side effect. With the exception of MAOI's, the table seems to be relatively complete. The article can be found at Http://pharmacy.orst.edu/dur/news/2_3/2_3.htm
>
> Hope this helps.
>
> By the way, a few observations I was able to make from the table in the article:
> (1) Sexual dysfunction side effect - attributable to all SSRI's and any other AD, such as Nardil, which inhibit the reuptake of serotonin.
>
> (2) No sexual dysfunction side effect - attributable to drugs which either block 5HT2a post-synapse (that is, do not allow the serotonin messenger to pass it's message along), e.g., Serzone. Also for drugs which exhibit little or no 5HT2 effect, such as Bupropion, venlafaxine, Mirtazapine, and Reboxetin
>
> (3) Weight gain side effect - any drug which acts upon 5HT2c, thereby stimulating appetite. These drugs include Mirtazapine and, I suspect, Nardil, as well.
>
> JB
poster:Daveman
thread:57775
URL: http://www.dr-bob.org/babble/20010327/msgs/58003.html