Posted by phillybob on March 21, 2001, at 19:57:04
In reply to Re: current Lamictal trials in action » phillybob, posted by JahL on March 21, 2001, at 16:48:45
Hey, Jah, hang in there, Friday's coming (a 70's expression, I believe). Friday'll be euthymia, for our purposes.
As far as titration, last week my pdoc explained how it would probably be okay to increase a bit faster because once past the beginning period, increases in dosage become a smaller percentage of the whole that one is taking.
In other words, in the beginning, a jump from 12.5 mg to 25 mg is a 100% increase. 25 mg to 50 mg is likewise a 100% increase. But, 50 mg to 75 mg then becomes just a 50% increase and 75 mg to 100 mg becomes a smaller 33% increase, etc., etc.
I also read somewhere that the first month is most important so that the body can acclimate to the drug. Once getting through that first month of adjustment, the likelihood of developing the rash is quite small. So, I've read, at least.
Nonetheless, I met with the pdoc tonight, and I'm gonna sally forward with a 12.5 mg/day increase some time this weekend for a total of 37.5 mg/day. I am going to split the dosage, for now. 25 mg then 12.5 mg later.
The pdoc has also more or less given the thumbs up to increase that to a total of 50 mg/day a bit quicker than we had been going, and then hang out there for a bit.
Yep, it's frustrating, this patience thang. I find that the not complete positive effects that I have kind of wear off by the afternoon. Perhaps, the higher doses will make it last for the day and perchance make me all better. Patience.
poster:phillybob
thread:55442
URL: http://www.dr-bob.org/babble/20010319/msgs/57101.html