Posted by Lorraine on March 16, 2001, at 11:35:46
In reply to Re: Report of success: Selegiline: alernate MAOI, posted by Adam on March 15, 2001, at 18:31:00
Wonderful post. Raises lots of questions. First off, I also had a very quick response to Selegiline--within an hour. It may be the amphetamine aspect of the drug that did this.
{ I have had Neurontin (gabapentin) prescribed for selegiline-induced insomnia and anxiety. I think this is a reasonable choice, given Neurontin's relatively benign side-effects profile at low doses. I have chosen not to take it though, and have rather focused my efforts on "sleep hygene" and exercise.}
Please tell me more about this. My sleep hygene is excellent, although without the Neurontin it might be a problem. On the other hand, maybe GABA alone could handle it. I stay on the Neurontin (900 mg a day divided into 3 doses) because it gives me a level of "mood support" I did not get from the Selegiline alone. What is your exercise component? Do you exercise each time you take a dose--although you are on the patch so perhaps your "ride" is smoother.
{a pharmacological approach second. Another approach that might be worth exploring is low-dose risperidol.}
Do you know anything about risperidol? Neurontin is not taking away my physical anxiety (tightness in chest, difficulty taking in a deep breath). I was thinking perhaps a beta blocker.
{Clearly, these metabolites do something, though, and I believe (being a non-expert, mind you) that their effects are mostly a nuisance which is mitgated considerably by transdermal delevery, which moderates both the rate of dosing and eliminates first-pass metabolism, whence much of the L-methamphetamine (the precursor of the L-amphetamine in this case) is generated.}
Does that mean that you are not "speeded up" on the patch?
poster:Lorraine
thread:56408
URL: http://www.dr-bob.org/babble/20010310/msgs/56663.html