Posted by jb on March 13, 2001, at 21:52:28
In reply to Much needed advice.., posted by Mr. Scott on March 12, 2001, at 9:51:31
Hi, Scott. I have pretty severe social phobia - making presentations in front of groups, that kind of stuff. The first meds I was prescribed were Nardil and Klonopin. This was 8 years ago: before everyone had the Internet. I was totally uninformed about what it was and what it did. Nardil worked wonders for my social phobia. It's also a powerful anti-depressant. It does tend to cause sexual dysfunction. Parnate, on the other hand, is also a non-selective MAOI (that is, it non-selectively inhibits both types fo MAO, A and B). However, it is a non-hydrazine MAOI, and Nardil is a hydrazine MAOI. They have different levels of efficacy and different side effect profiles. Parnate is more stimulating and has less of an effect on sexual function.
Selegiline, on the other hand, is mostly used at 10-15 mg/day, where it remains selective for MAO-B, thereby mostly affecting dopamine. I'm not aware of many studies of its efficacy for depression at higher dosages. I did take it at 60 mg/day, perhaps for too short of a time period, hoping it would have an effect similar to Nardil, but without Nardil's side effects. I didn't get that, but, again, perhaps my trial was too short.
Also, I wouldn't be worried about any dietary restrictions, etc. Selegiline at 15 mg/day had few, if any, I believe. While I was and continue to be on Nardil, 60 mg/day, I rarely follow the dietary restrictions. I only stay away from red wine, which causes me a slight headache. I eat pizza like crazy and drink regular or lite beer. No dark beer. I also use blue cheese dressing, etc.
Good Luck.
John B
poster:jb
thread:56285
URL: http://www.dr-bob.org/babble/20010310/msgs/56450.html