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Re: treatment resistant depression » allisonm

Posted by sweetmarie on March 7, 2001, at 16:40:58

In reply to Re: treatment resistant depression, posted by allisonm on March 7, 2001, at 15:48:00

> I have been diagnosed with chronic treatment resistant depression. I have tried Zoloft and Effexor XR but was not able to tolerate either. I was on Remeron for more than 2 years, then Remeron and lithium, then Remeron and Wellbutrin, then Wellbutrin and Remeron, then Wellbutrin and Neurontin, then Wellbutrin, Neurontin and Celexa. Am having to drop Celexa because I cannot stop shaking and it is causing sleep problems after more than a month. Next trial will be Wellbutrin, Neurontin (I think) and Serzone once I get off the Celexa. I haven't had as many years as you have trying drugs, but know exactly how you feel. With each new failure is the increasing feeling that I will never find the answer. I am surprised that your doctor(s) haven't tried Remeron and Effexor together before now, however, as this is known to be quite effective. There is an eGroups page on Remeron that will have references to its use with Effexor. Good luck.

I feel reassured that I am not the only one having difficulties with medication treatment. The specialist I was referred to intends to try a combination of Venlafaxine, Mirtazapine and wants me to remain on the Lamotragine but at a (much) higher dose. To do this he wants me to be an in-patient at his hospital in Newcastle (about 150 miles away from where I live) because it will both speed the transition up, and be a support as coming off Phenelzine is notoriously difficult - I am likely to be quite ill (i.e. even more depressed). I am glad to be coming off the Phenelzine, as it has made me gain 3 stone. However, apparently the Mirtazapine that I am going onto has weight gain as a possible side effect. Obviously, if the treatment `works` then I won`t mind so much being overweight, but it doesn`t do my self-esteem any favours at the moment. As for Remeron, I could be wrong but I have a feeling that it is the trade name for Mirtazapine in the States (it`s Zispin over here). Anyway, I`ll have to wait and see. I do agree though that it`s very easy to get into a real `spiral` of depair when nothing seems to work (even when assured by all sides that there is `something for everyone`). I hate to admit it, but I find myself resenting those who seem to `take to` anti-depressants with such success, although I realise that this is not a fair way to see things.
Thanks for replying - keep me updated (if you want). Good luck to you, too.


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poster:sweetmarie thread:55847
URL: http://www.dr-bob.org/babble/20010302/msgs/55863.html