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Re: Ziprasidone (Zeldox) Approved ! - SLS

Posted by JohnL on February 8, 2001, at 4:40:42

In reply to Ziprasidone (Zeldox) Approved !, posted by SLS on February 6, 2001, at 10:03:19


Hi Scott,
I was just curious. Since I respond well to antipsychotics in general, I am curious in learning more about Zeldox. Beyond the known benefits of fewer side effects, do you know how Zeldox differs from Zyprexa?

For example, while Zyprexa works on both serotonin and dopamine receptors, it is actually weighted proportionately a little stronger toward the serotonin side. I wonder if Zeldox is weighted the same, or whether it is stronger on dopamine. And what about the antihistimine part of it? Same as Zyprexa? Different? Sedating or not? Any idea if Zeldox blocks presynaptic dopamine, postsynaptic, both, or differing depending on dose size?

I'm just curious at how Zeldox and Zyprexa differ in mechanism, on paper anyway.

Thanks in advance!
John

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poster:JohnL thread:53408
URL: http://www.dr-bob.org/babble/20010131/msgs/53496.html