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Re: Topamax Experiences?

Posted by Bob on January 21, 2001, at 22:24:33

In reply to Re: Topamax Experiences?, posted by phillybob on January 21, 2001, at 21:19:58

> Hi, kids! Back from my NYC trip. Great time! (business and pleasure). 200 mg/day (100 mg am and 100 mg pm). Just pushed it to 250 mg/day today (125 and 125) as I've kind of felt like I could use a tweaking it up a tad. I don't know.
>
> These numbers we often are shooting for seem so arbitrary considering we patients come in all shapes and sizes. And then compound that with the fact that this drug happens to be approved only as an anticonvulsant right now, and we're usin' it for something entirely different! I did though just now on medscape see it referred to as a NEUROMODULATORY drug. I kind of like that one.
>
> Still not taking anything else except I have added a B-Complex Stress thing-a-ma-tab (B12,folic acid, etc.) to help with the tingles (face, finger and toe tips) and it has.
>
> And, Bob, I had, for the first time, since New Year's Eve, a couple of beers last night, and today did not seem to have the tremedously untoward effects that I did that time. Maybe, once adjusted to the drug, alcohol in moderation is okay? Hmmmm. Anyone else want to add?
>
> Still get the old visual disturbances (eye pressure?) typically in the morning and fairly often. Anyone else?
>
> Not much weight loss to speak of. Less food cravings and binging at times, but other times not. Overall, perhaps some weight loss due to less alcohol, more exercise/activity (due to less depression), and somewhat more overall eating stability.
>
> Overall, I'm pretty satisfied with my 3 plus weeks of topiramate monotherapy. Lamictal add-on is always an intriguing one. Damn that Lexie, filling me with those novel ideas! :) (jes' kiddin' of course 'bout damnin' Miss Lexie)

**********************

phillybob,lexie,etc...

I'm up to 100mg BID 50mg am, 50mg pm for about a week now, and have been on topo for about a month total. I too am getting the tingling. It is starting to get prominent in my hands and wrists - especially towards the outer parts of my hands. I even get a little bit of it in my heels! I imagine if I end up working up to 250mg like you phillybob, I will be getting much more tingling. The blurry vision has died down for the most part, as has the rash; but again, I'm sure it would all be back with dose increases. I have started to feel a little bit of what seems to be a lifting of depression maybe??? Could it possibly be? It also seems like I could be getting a slight bit of relief from my anxiety and muscle tension troubles. I am still taking trace amounts of Celexa and T4 in the am (10mg and 12.5mcg respectively) and have been withdrawling from those. I think as a result I have been experiencing more emotional lability than I would normally be encountering had I been stable on a med, and just added tompirimate. The reason I'm mentioning this, is because it unfortunately makes it hard to assess what feelings and effects are a result of the topo and what are a result of the other meds. Oh well... one day at a time. I'm have hope that this topomax may have something promising for me in the future. I just hope that it can have a good AD effect without the need to augment it with further meds.

Bob

 

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