Posted by anita on November 15, 2000, at 17:23:57
In reply to Poll regarding Prozac response and nonresponse, posted by anita on November 8, 2000, at 19:42:59
Hi all,
Thanks so much for responding to my poll. I asked about these meds because I am wondering if a lack of response or a poor response to Prozac might indicate that the other meds might be helpful. While Prozac does not downregulate 5HT2 receptors, the other drugs do (tho I'm not sure about Neurontin, and I should have added Serzone to the list). Given the conflicting studies on whether depressives have increased or decreased 5HT2 receptors, I think there may be two subsets of depression (among many other subsets), one with decreased 5HT2 function and one with increased function, which would respond (at least partially) to only one group of antidepressants.
So, theoretically, if Prozac did not work, or if it worked only partially, and you had increased 5HT2 receptors, the other meds listed could help alleviate your depression.
anita
> Hi,
>
> I'd like to find out if people who had no response or a negative response to Prozac had a good response to any of the following meds:
>
> Zoloft
> Lamotrigine
> Neurontin
> Risperidone
> Zyprexa
>
> Conversely, I'd like to know if people who had a good response to Prozac had no response to the above meds.
>
> Thanks very much for your input.
>
> anita
poster:anita
thread:48467
URL: http://www.dr-bob.org/babble/20001115/msgs/48866.html