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Re: clorgyline - The Agony and the Ecstasy » rogdog

Posted by SLS on October 2, 2000, at 19:41:52

In reply to clorgyline, posted by rogdog on October 2, 2000, at 16:19:13

> DOES ANYONE KNOW WHERE IN THE HELL TO GET CLORGYLINE!!!!!!?????????


Rogdog, this is probably the most important question I have seen asked on this board with regard to clinical treatment.

Clorgyline is the most potent MAO-inhibitor available, and is, in my view, the most efficacious antidepressant in the world.

Clorgyline is no longer being manufactured for human consumption anywhere in the world. I don't believe that it was ever marketed anywhere. The chemical company has been contracted to produce clorgyline for research purposes only: as a biological probe, for in vitro work, for assay work, and for animal experiments.

Those damned rats don't know how lucky they are. If we persevere, perhaps we can develop a taste for clorgyline-treated rats.

I am looking for some suggestions on how to go about petitioning for the development of this miracle for human clinical application. One of the problems is that the patent probably expired a long time ago. What is the incentive for a drug company to start from scratch, spend 13 million dollars for development, devote 3-5 years to get it approved, only to have a generic drug manufacturer say to the FDA, "Me too".

Sorry for the bad news. I have been agonizing over this for the last 8 years.

I took clorgyline for about a year. Easily the most potent single drug I have ever been on. Unfortunately, the FDA did not allow for clorgyline to be combined with any drug other than lithium. I am all but sure that a sprinkle of desipramine would have prevented you from reading this.


- Scott

 

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