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Re: Giving up reboxetine, what's next?(long)

Posted by JohnL on September 13, 2000, at 4:51:56

In reply to Giving up reboxetine, what's next?(long), posted by Anna P. on September 12, 2000, at 11:18:38

Anna,

I sure wish there was an easier way. But it sounds to me like you are brave, strong, determined, and well researched. Those qualities will all help you on the road to recovery.

I wish I had some kind of medication advice or suggestion for you. The best I can figure at this time is that if Reboxetine worked for a while but then faded, that gives clues toward two things:
1) Low Norepinephrine chemistry. A good response to Reboxetine proved this.
2) Some chemical or electrical instability. The fading of a good response proved this.
With these clues in mind, I think your idea of Lithium is a good one. You might be able to stay with Reboxetine, but just add Lithium in the 300mg to 900mg range, maybe 1200mg tops. Another possibility would be to switch from Reboxetine to one of the older tricyclics. They work mostly on norepinephrine. My two favorites in that category are Nortriptyline and Desipramine. You may respond very well to one but not the other, so you might have to try them one at a time to see. These older tricyclics do come with side effects like dry mouth and constipation, but they were always and still are very good antidepressants.
I wouldn't put too much hope into Inositol or Pindolol, though anything's possible.
John


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poster:JohnL thread:44679
URL: http://www.dr-bob.org/babble/20000905/msgs/44737.html