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Re: Reserpine for treating depression ?

Posted by Sunnely on July 28, 2000, at 0:39:09

In reply to Reserpine for treating depression ?, posted by SLS on July 27, 2000, at 10:33:56

> Does anyone know anything about the use of reserpine in the treatment of depression?


Reserpine is used primarily as an antihypertensive drug, although reports of its use in the treatment of psychosis date back to ancient Hindu Ayurvedic texts. Reserpine was used to treat psychosis before the introduction of antipsychotics in the 1950s.

Once known for its role in causing depression, reserpine has been suggested as effective for depression when given in combination with tricyclic antidepressants. Several studies showed benefits from the use of reserpine and TCAs but more recent studies, however, have placed a question mark on these benefits.


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