Posted by shellie on June 29, 2000, at 23:06:16
In reply to Re: MAOI...Shellie, posted by janeS on June 29, 2000, at 13:55:53
> Thanks for your input. Can you tell me what kind of augmentation with Nardil you're doing this second time around?
>
> JaneHi Jane. I'm trying to augment nardil with provigil. This is my second try with provigil. The first time I started with two high a dose and got really nauseated. So I stopped and after I felt better started again--two days ago, much slower--so far no problems.
I'm going to give you all the information that I gathered since January, when I felt the nardil lost effectiveness, since some part of it may be helpful to you. I'll try to condense.
In Feb did a trial of sam-e with Nardil, with on the phone supervision with a physician affiliated with Columbia U. who wrote a book on sam-e. He gave sam-e a 70% change of working. Unfortunately, it was not good for me--it made me more depressed and very agitated. But if you look at the sam-e board at www.delphi.com a lot of people who had tried lots of prescription meds, had enormous success with it.
He also said if the sam-e didn't work, these would be his recommendations to try with nardil:
1. thyroid, add 25 mc of cytomel (t3) for 2 weeks; can try 37.5 also
***2. lamcital- (anti-seizure medication) have to go up very very slowlyÑover a 3 month period--
3. add very low lithium level (works 50% of time)Ñ
4. add traxedone (deserel)
5. add pindolol
6. add ridlinBecause my pdoc was unwilling to experiment, I also consulted with a pdoc at NIMH by phone (very helpful) and with my old pdoc, who was no longer accepting my insurance.
The first choice of all three was lamictal. In the last" MAOI doesn't work anymore" thread, I explained that lamictal worked for me really well, but I was gaining weight. A very small percent of people gain weight on lamictal. I was unlucky and unwilling to accept a weight gain since there were other things for me to try. But I think it is very significant that all three doctors I consulted with, picked that as their first choice.
I'm surprised I don't read anything about it on this board, because knowlege of its success is well known, at least in Washington D.C. (where I am) and New York City.
I then returned to my old pdoc and pay out of pocket. After lamictal, her second choice for me was naltrexone (revia)--I tried it for one day and felt too drugged and weird.
Because she thought ridlin (sp?) would overstimulate me, we decided next on provigil. She wants to look into adrafinil before I order it, since I would like to try that if the provigil is not successful. After reading about two very very small studies of provigil augmentation with a 100 percent success rate (N = 7 for one, I can't remember the other, also very small) I am feeling hopeful.
btw, I was already taking thyroid, t2 & t3, and had already been unsuccesful with lithium.
Sorry this is so long--I am apparently not a successful condenser--but I thought giving you all the information might be useful.
Shellie
poster:shellie
thread:38324
URL: http://www.dr-bob.org/babble/20000619/msgs/38781.html