Posted by SLS on June 29, 2000, at 7:20:10
In reply to Re: Sulpiride - Anna, posted by KarenB on June 28, 2000, at 20:41:56
Dear Karen,
> When I took Sulpiride, it was under the brand name Dogmatil. Is that what you have? If so, I took one capsule, 3x a day. I took it along with a psychostimulant, Amineptine, which is sadly no longer available. A possible alternative psychostimulant might be Adrafinil, 300mg 2x a day. The max recommended for fatigue/depression is 300mg 4x a day. I will trial this soon and plan to split the tabs and start with 150mg, 2x a day and work up after a few days. Adderall is another possibility.
I just started taking sulpiride. The brand name is Sulparex, and I am getting it from a pharmacy in London. I have been taking 50mg of sulpiride in the morning for the last 6 days. I think I feel a slight improvement for the first few hours after taking it, but it disappears quickly. I am getting impatient because my doctor wants me to continue taking 50mg for another week. I want to feel better yesterday.What was the total dosage of Dogmatil that you took?
What dosage did you start with, and how did you increase it?
Are you still taking Dogmatil?
I wish you the best of luck with the adrafinil. If adrafinil is similar to modafinil (Provigil), it probably helps to increase the activity of dopamine neurons in the areas of the brain involved with motivation and reward. Dogmatil may exert its antidepressant effects by activating the same areas, but in a different way. Combining sulpiride and adrafinil sounds like a very good strategy.One thing that I would like to mention is that JohnL has described that adrafinil has a "therapeutic window" for him. There is a dosage that is just right - not too low and not too high. After he began to respond positively at a certain dosage, he tried to increase it further. After the increase, he began to feel less well. When he reduced the dosage back to what it had been before the increase, he felt well again. This may not necessarily be the case for you, but it is something to be aware of.
Good luck. I hope to be able to watch you get well.
Sincerely,
Scott
poster:SLS
thread:31704
URL: http://www.dr-bob.org/babble/20000619/msgs/38674.html