Posted by SLS on May 18, 2000, at 16:56:38
In reply to Re: COMTs as substitutes, posted by AndrewB on May 18, 2000, at 16:05:34
Hi Andrew.
Please keep us informed as you progress through your trial of entacapone. I hope you get out of it what you are looking for. Although it hasn't seemed to be very potent as an antidepressant when used monotherapeutically, it looks like a good drug to combine with the other dopaminergics that you mention. Combining entacapone with amisulpride is an intriguing proposition. One other strategy mentioned by PeterJ was to add l-dopa (Sinemet) to a COMT inhibitor.Q: You seem to be experimenting with quite a few drugs. Have you ever felt satisfactorily well on any drug regimen? What residual symptoms have not been adequately treated?
Perhaps Cam W. can comment on any drug interaction concerns with the use of entacapone.
I am eager to hear that you do well on your new adventure. Good luck!
Oh, I almost forgot. My doctor told me yesterday that Sanofi-Synthelabo is now intested to bring amisulpride to the U.S.
Sincerely,
Scott
poster:SLS
thread:33419
URL: http://www.dr-bob.org/babble/20000517/msgs/33928.html