Posted by AndrewB on April 7, 2000, at 12:22:54
In reply to Re: a couple questions for FP..., posted by CarolAnn on April 7, 2000, at 8:03:17
Diane,I am the one who told you you could order buprenorphine from Vitality. I'm sorry if it didn't get through. As you know, Vitality has been shut down by Thai authorities. If your buprenorphine was siezed by customs you should have received a notice from them. If you did not receive a notice it is more likely that your medicine was 'lifted' by a postal employee.
There is another non prescription source of buprenorphine, please email at andrewb@seanet.com for this information.
I researched a little on the web and one site suggested that a mood stabilizer may help you even though you are unipolar. The information is old and maybe off base but never the less I think you'll find the site interesting, see below.
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http://www.druglibrary.org/schaffer/heroin/methadone/selfmed.htmAnnals New York Academy of Sciences, 1982. V.398 pp 44-53
METHADONE AND OPIATE DRUGS: PSYCHOTROPIC EFFECT AND
SELF-MEDICATIONGerald J. McKenna
In 1977 and 1978 Gold et al.22, 23 reported on the dopamine-blocking action of methadone as evidenced by the increase in serum prolactin following administration of methadone. They point out that neuroleptic agents such as haloperidol inhibit the enzyme dopamine-stimulated adenylate cyclase. Methadone and other opioid drugs apparently do the same. They postulate that for this reason "opiate agonists may be antipsychotic in man." Kleber and Gold in 1978 documented well the various uses of psychotropic drugs in the treatment of narcotics addicts on methadone maintenance. The administered lithium carbonate to a group of patients on methadone maintenance with a history of recurrent depression but no history of manic or hypomanic episodes. The allowed the patients to decrease their methadone dose while on the lithium trial and found that the methadone dose decreased significantly (p<0.01) during the trial. They provide support for the hypothesis that methadone is antipsychotic and antimanic and suggest an endorphin hypothesis for the mechanism of action of lithium. They also document the use of neuroleptics in schizophrenic patients maintained on methadone as a result of their opiate dependence. The state, "With the recent developments in opiate receptor and peptide identification reexamined clinical data suggest that opiate receptor activity and opiates may be psychotomimetic and antipsychotic respectively." The antipsychotic properties of methadone are hypothesized on the basis of opiate agonist receptor activity, i.e., interference with the postsynaptic action of dopamine, the mechanisms espoused for the antipsychotic actions of traditional neuroleptic drugs.
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poster:AndrewB
thread:28647
URL: http://www.dr-bob.org/babble/20000401/msgs/29194.html