Posted by UniVerSity on April 5, 2000, at 15:39:04
I've been on Prozac for 7 years, and during the last four, I have suffered from a general apathy that lends itself to hypersomnia, indifference about things, and lack of creativity/motivation.
But Prozac *has* kept depression at bay, and I am very thankful for that. I am reluctant to switch to another AD because Prozac is primarily effective for me, and I don't want to risk an episode of depression that might not respond to anything (although I have no history of treatment-resistance).
So I've tried several things to address the problem. Believing that my apathy may be due to dopamine downregulation, I have tried augmenting Prozac with: Wellbutrin, Ritalin, desipramine, and Amantadine.
Honestly, I didn't give Wellbutrin a fair trial, but quit it after a couple of weeks of jaw pain and anxiety. Amantadine took me to the threshhold of depression after one day, so I quickly discontinued it. Desipramine didn't have any effect except for increased sweating and retrograde ejaculation.
Ritalin--the most effective--gave me euphoric feelings that abated after a week, and seemed dose-dependent.
Any advice? I might try Wellbutrin again, and give it a month at a good dose.
TIA,
JM
poster:UniVerSity
thread:28969
URL: http://www.dr-bob.org/babble/20000401/msgs/28969.html