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Re: Pivagabine

Posted by AndrewB on March 6, 2000, at 23:39:40

In reply to Re: Pivagabine, posted by ryan_s on March 6, 2000, at 22:46:40

> hopefully someone can help. is a CRH antagonist similar to that of the antidepressant that combated substance P? andrew or brad, have either of you tried tianeptine, and if you did how was your experience. thanks
>
> ryan_s

Ryan,

I don’t think CRF antoagonists and NK1 (Substance P) receptor antogonists have anything in common other than they act on the HPA axis.

Yes I did try tianeptine. I didn’t give it fair trial though. I used it for only five days. I felt so unsociable, like a sociopath, like a wolf amidst sheep. I thought....this is scary, I’m quiting this stuff. There was a poster back in May who said he had been taking tianeptine for 5 months. I suggest you go back in the archives and read his post, his name was Pandey M. He said that it lowered cortisol amoung other things. He said it wasn’t great for depression but that it helped with panic attacks even though it induced a separate kind of nervousness. It also made him less sociable.

AndrewB


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