Posted by Rick on January 20, 2000, at 14:40:18
In reply to Benzodiazepenes - Social Anxiety, posted by Doug on January 20, 2000, at 13:40:17
Absolutely, but longer-acting Klonopin (clonazepam) works SOOO much better for me than Xanax. And since it IS longer acting, it doesn't need to be taken as often and, for most people, allows easier withdrawal. Some people will debate me on this, but read the literature, especially this MEDLINE abstract from a major placebo- controlled study (few studies show a medication response rate THIS high; and a similar study for Xanax was inconclusive):
J Clin Psychopharmacol 1993 Dec;13(6):423-8Treatment of social phobia with clonazepam and placebo.
Davidson JR, Potts N, Richichi E, Krishnan R, Ford SM, Smith R, Wilson WH
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710.Clonazepam and placebo were administered in a double-blind pilot study to 75 outpatients with social phobia. The mean maximum dose of clonazepam was 2.4 mg/day at endpoint (range, 0.5 to 3 mg). Treatment was continued for up to 10 weeks. The results of an intent-to-treat analysis indicated superior effects of clonazepam on most measures. Response rates for clonazepam and placebo were 78.3 and 20.0%. Drug effects were apparent on performance and generalized social anxiety, on fear and phobic avoidance, on interpersonal sensitivity, on fears of negative evaluation, and on disability measures. Significant differences were evident by week 1, 2, or 6, depending upon the rating scale used. Clonazepam was well tolerated in general, although unsteadiness and dizziness were more severe and persistent than was the case for placebo subjects.
Publication Types:
Clinical trial
Randomized controlled trial
PMID: 8120156, UI: 94165219----
> Just curious, I have had success with taking a dose of 1.125 to 1.25 mgs of Xanax an hr. or so before anticipated social anxiety situations (presentations, staff meetings, etc.) do you think regular lower doses throughout the day would have the same effect ? (takes the fidegting, nervousness, edginess, etc away)
poster:Rick
thread:19267
URL: http://www.dr-bob.org/babble/20000112/msgs/19273.html