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Re: Antidepressants

Posted by JohnL on July 26, 1999, at 15:02:21

In reply to Re: Antidepressants , posted by Jamie on July 26, 1999, at 13:52:26

I am taking Prozac w/Wellbutrin. I would think this combo would be more activating than it is. No sedation like so many others though. Hard to say if you'll have weight gain. Theoretically you shouldn't. Anorgasmia likely, but there is a way to help with that. Insomnia likely, also a way to help. First, for insomnia, a small dose of Remeron or maybe Trazodone will let you sleep, and boost the Prozac as well, perhaps allowing you to go with less than 60mg. For sex, the Wellbutrin helps me a lot, especially for drive. Also, there is a theory that the steady state of Prozac (fluoxetine) is what causes the sex problems, and that its metabolite (norfluoxetine) doesn't. Both are equally active on serotonin, and the half life of norfluoxetine is about a week. So, the theory is to dose once every two, three, or more days rather than daily. The theory seems to be working fine with me. Maybe you would be fine with 40-80mg every two days? Worth a try? I do 40mg every two days and have great sex. It does take longer, but it ends with a fireworks, not a whimper like other drugs did. Another consideration might be Naltrexone, which for some people who took 80mg Prozac a day allowed them to go all the way down to 20mg and be better than ever. I don't think there is a way to eliminate all side effects, but these are some ways to treat them and boost the antidepressant treatment simultaneously. Prozac is very flexible for manipulation. Hope this helps? JohnL.




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