Posted by Wayne R. on May 19, 1999, at 13:04:10
In reply to Heck with the clinical term -- what does it mean?, posted by Mare on May 14, 1999, at 16:07:49
Mare,
In Dr. Bob's Psychopharmacology Tips there is a set of articles titled "Patients who lose response to antidepressants". These postings were made by psyc docs. In addition to poop out I also noticed a reference to dosage creep. Here are two lines extracted from that item:
I have often observed that patients who respond well to low doses of an antidepressant... lose the effect after a month or so....
This is now spoken about in many psychopharm conferences as "poop out." In my experience it sometimes happens as late as 3 years into an SSRI (typically Prozac, since it's been around the longest), in as many as 20% of patients.
Wayne
poster:Wayne R.
thread:6095
URL: http://www.dr-bob.org/babble/19990501/msgs/6268.html