Psycho-Babble Medication | about biological treatments | Framed
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Re: Dr. Bob & others - your opinion re SSRIs

Posted by sean on February 24, 1999, at 20:08:02

In reply to Dr. Bob & others - your opinion re SSRIs, posted by paul frank on February 23, 1999, at 19:19:26

> I suffer from GAD with some symptoms of depression. My doc first put me on prozac 20mg. After 4 weeks, the depressive symptoms had improved, but the anxiety continued, so she switched me to Zoloft. I have been at 100 mg for two weeks now and depressive symptoms have not returned, but I remain anxious and worried. I have had minimal side effects from both drugs, other than excessive nervousness. In your opinion, if Zoloft doesn't work, should we go to a third SSRI (my doc says she will next try Paxil) or would it make more sense to switch to another class of anti-depressant (ie Effexor? Serzone?) My main problem has always been GAD.
> Thank you for your response.

I had good luck with amitriptyline in my 20's. It
really helped with anxiety and insomnia. I did not
notice the personality effects which happen with
SSRI's. Some people like the personality changes
that can occur with SSRI-class drugs; I find them
interesting, but shallowing overall. They also
make me sleepless and manic so, I have a problem
balancing the SSRI's.

If you can hack the
anticholinergic effects of a TCA, they are a well
studied, effective, and venerable class of meds
that have really helped alot of people. Apparently
amitriptyline is more anxiolytic than say,
desiprimine due to higher serotonin binding
(relative to dopamine)It also has a general
sedative effect which some people like and others
loathe... Good luck,





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