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NRIs are infact dopamine uptakin inhibitors ?

Posted by linkadge on February 19, 2006, at 18:19:26

Is this true ??


The effect of NSRIs on serotonin and dopamine may be explained by the observation that norepinephrine, acting through alpha1 receptors, can induce release of these transmitters (54). However, in addition, the norepinephrine transporter protein—the reuptake site—also has high affinity for the reuptake of dopamine (56). Thus NSRIs are, in effect, dopamine reuptake inhibitors as well.





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