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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Jimmyboy on January 17, 2007, at 10:11:26
Another question .. for you biochem folks out there.
Is there any connection between glutathione levels and increasing BDNF ( hippocampal)or any other neurptrophic factors ?
Is more glutathione a good thing for your brain, I know it is, but why exactly?
ThanksJB
Posted by Larry Hoover on January 21, 2007, at 10:20:39
In reply to 1 more academic ? for you biochem enthusiasts., posted by Jimmyboy on January 17, 2007, at 10:11:26
> Another question .. for you biochem folks out there.
>
> Is there any connection between glutathione levels and increasing BDNF ( hippocampal)or any other neurptrophic factors ?Yes.
Oh, the nature of that relationship? ;-)
Higher glutathione levels stimulate BDNF release, which is dependent on ascorbate concentration.
> Is more glutathione a good thing for your brain, I know it is, but why exactly?
>
>
> Thanks
>
> JBGlutathione is one of the free-floating scavengers of ROS (reactive oxygen species). Oxygen may be required for life, but it is arguably the most reactive of all elements. Our bodies are playing with fire, literally. Byproducts of normal reactions often include the formation of some very reactive debris. Glutathione has a terminal sulfhydryl group, which reacts readily via oxidation. So, it's a sacrificial lamb, hopefully taking the ROS bullet instead of your precious membrane polyunsaturates, or DNA, RNA or proteins.
Glutathione formation is cysteine dependent, which is why whey protein is often recommended.
Lar
Posted by Jimmyboy on January 21, 2007, at 22:59:44
In reply to Re: 1 more academic ? for you biochem enthusiasts. » Jimmyboy, posted by Larry Hoover on January 21, 2007, at 10:20:39
Larry,
Thanks for the good answer. Do you know if regular whey protein would work or if you need to get the super expensive CFS targeted brands that are "undenatured" like " Immunepro" or Immuneplex" ?
Thanks
JB
Posted by Larry Hoover on January 22, 2007, at 8:01:15
In reply to Re: 1 more academic ? for you biochem enthusiasts. » Larry Hoover, posted by Jimmyboy on January 21, 2007, at 22:59:44
> Larry,
>
> Thanks for the good answer. Do you know if regular whey protein would work or if you need to get the super expensive CFS targeted brands that are "undenatured" like " Immunepro" or Immuneplex" ?
>
> Thanks
>
> JBI don't know anything about these expensive brands, or what they could mean by undenatured.
Many protein supps are hydrolyzed. That just means pre-digested, and inherently any proteins remaining are likely denatured. To be undenatured would imply that they are not hydrolyzed? If so, just get some whey protein powder (e.g. bulkfoods.com), and let your body at it.
I have to go out, but when I get back, I'll try and figure out what mystical attribute those fancy brands are trying to sell.
Lar
Posted by Larry Hoover on January 22, 2007, at 9:53:47
In reply to Re: 1 more academic ? for you biochem enthusiasts. » Larry Hoover, posted by Jimmyboy on January 21, 2007, at 22:59:44
> Larry,
>
> Thanks for the good answer. Do you know if regular whey protein would work or if you need to get the super expensive CFS targeted brands that are "undenatured" like " Immunepro" or Immuneplex" ?
>
> Thanks
>
> JBI cannot see any evidence for enhanced benefit from using these expensive products. I read about a "study" that Cheney did, but it was open (participants knew what they were taking), did not involve denatured whey (no comparison group), had only eight subjects (totally insufficient sample size), used unverified measures of efficacy, and used no control subjects of any sort. Somehow, they concluded that this expensive stuff was the real deal.
Hogwash.
They argue that if this stuff is taken on an empty stomach, there is no stomach acid (which denatures and hydrolyzes proteins) to consider. Hogwash. Only if a person has achlorhydria (lack of stomach acid production, a medical disorder), would this be the case.
My BS detectors are going off all over the place.
Lar
Posted by Jimmyboy on January 23, 2007, at 14:08:25
In reply to Re: undenatured whey » Jimmyboy, posted by Larry Hoover on January 22, 2007, at 9:53:47
I thought that had to be BS too!To charge that much and take advantage of CFS patients, (who have vague symptoms and can not get any answers from the medical field).. is dispicable , I think .
JB
Posted by tealady on January 23, 2007, at 16:10:45
In reply to Re: undenatured whey, posted by Jimmyboy on January 23, 2007, at 14:08:25
>
> I thought that had to be BS too!
>
> To charge that much and take advantage of CFS patients, (who have vague symptoms and can not get any answers from the medical field).. is dispicable , I think .
no.. it's the American way ? capitalism?
max out profit?
Posted by guardianangel on January 26, 2007, at 13:12:23
In reply to Re: undenatured whey » Jimmyboy, posted by tealady on January 23, 2007, at 16:10:45
Glutathione's sulfhydryl groups make it a powerful chelator of endemic neurotoxins like mercury, cadmium and lead which otherwise supress Long Term Potentiation (laying down of memories) in the hippocampus. Presumably it can help get rid of other "brain drain symptoms" a.k.a. erethismus or loss of social confidence and mental articulation from micromercurialism. To that end there is bound to be a downstream effect on brain derived nerve growth factor...
Posted by KayeBaby on February 1, 2007, at 14:16:04
In reply to Re: undenatured whey » Jimmyboy, posted by tealady on January 23, 2007, at 16:10:45
Capitalism is fundamentally about individual rights and not exploitation as you seem to imply.
In economics it refers to privately or corporately held capital and a system that that operates under a free market.
We are participating in a laissez-faire environment reflective of capitalism right here in this forum.Dr. Bob owns the site so he strikes the bargain and we are free to take it or seek a better option elsewhere.
I would say that Jimmyboy, having freely entered into an exchange with Dr. Bob and upon finding value in this barter would be a very good example of capitalism.
Capitalism is the system that gives the whey mercant the right to develop and sell his product it is also the system that supports the individuals in the process of deciding which product at what price suits them best.
This is off topic I am sure but you did ask, no?
Kaye
Posted by tealady on February 3, 2007, at 23:30:55
In reply to Re: undenatured Capitalism, posted by KayeBaby on February 1, 2007, at 14:16:04
>
> Capitalism is fundamentally about individual rights and not exploitation as you seem to imply.
> In economics it refers to privately or corporately held capital and a system that that operates under a free market.
>
>
> We are participating in a laissez-faire environment reflective of capitalism right here in this forum.
>
> Dr. Bob owns the site so he strikes the bargain and we are free to take it or seek a better option elsewhere.
>
> I would say that Jimmyboy, having freely entered into an exchange with Dr. Bob and upon finding value in this barter would be a very good example of capitalism.
>
> Capitalism is the system that gives the whey mercant the right to develop and sell his product it is also the system that supports the individuals in the process of deciding which product at what price suits them best.
>
> This is off topic I am sure but you did ask, no?
>
> Kaye
Dear Kaye,
Ya forgot the bit about perfect(100% full immediate with no effort.. bit like plugging oneself into a truthful memory bank) unhindered, unrestricted flow of knowledge, money, resources, product and rights...creating ,of course, a perfect platform for choice with full knowledge. oh, and of course, no effort required for the choice to be made!
Then yeah, you're right I guess ;-)..
oh know, I forget the environment and that it is not properly costed in.. sigh
Posted by KayeBaby on February 5, 2007, at 1:57:33
In reply to Re: undenatured Capitalism, posted by tealady on February 3, 2007, at 23:30:55
Blink, blink.
Peace,
Kaye
Posted by tealady on February 5, 2007, at 3:45:29
In reply to Re: undenatured Capitalism, posted by KayeBaby on February 5, 2007, at 1:57:33
> Blink, blink.
>
> Peace,
> Kaye
>
'
Peace Kaye :-)
couldn't help biting on that one.. and I was restrained ;-)
I didn't mention how lifestyle etc is not accounted for either..
have a read of this for instance..
http://www.jantea.blog.co.uk (the vanuatu post)
Vanuatuans were actually voted the happiest people on Earth.. how that vote was counted don't ask me.. of course that's b4 this started..Do your realise I actually think capitalism is the best system we have , LOL ?
of course I feel it needs a good dose of perspective for social/envirnomental/lifestyle considerations for the whole planet
.. and then there's the influence of marketing..
..sorry (no more I promise.. err economics was my first training at uni?)
Jan
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