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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by bipolarspectrum on July 26, 2006, at 20:32:53
hi,
I'm on 3000mg daily vitamin c for my bipolar II and its doing wonders! great mood, high productivity... im living again... but i feel kinda hypomanic, more like a constant mild hypomania... i was wondering if there was any other thing i could add that could calm me down a little??
bps
ps. im gonna try magnesium with it soon
Posted by dessbee on July 27, 2006, at 18:40:00
In reply to WOW vit C is workin for my bipolar BUT....., posted by bipolarspectrum on July 26, 2006, at 20:32:53
Fish oil has an anxiolytic effect and should be good for Bipolar disorders.
Posted by bipolarspectrum on July 27, 2006, at 22:53:33
In reply to Re: Fish oil, posted by dessbee on July 27, 2006, at 18:40:00
Posted by dessbee on July 28, 2006, at 5:54:42
In reply to Tried fish oil, made me MANIC! (nm), posted by bipolarspectrum on July 27, 2006, at 22:53:33
What type of vitamin C are you taking?
Posted by bipolarspectrum on July 28, 2006, at 9:40:05
In reply to Re: Type of vitamin C, posted by dessbee on July 28, 2006, at 5:54:42
Hey Des,
thanx for the reply... im taking regular vitmian c, nothing fancy... i tried extended release vitamin c but i felt it gave me diarrhea...
bps> What type of vitamin C are you taking?
>
>
Posted by Tomatheus on July 28, 2006, at 13:17:45
In reply to WOW vit C is workin for my bipolar BUT....., posted by bipolarspectrum on July 26, 2006, at 20:32:53
bps,
The magnesium may help make you feel a little bit more calm. Another thing that you might want to consider is lowering your dose to 2,500 mg or perhaps 2,000 mg to see if that might make you feel more euthymic, as opposed to hypomanic.
If you don't mind me asking, what other meds/supplements are you taking? I'm just wondering because it may be possible that the vitamin C could be acting (a bit too) synergistically with one or more of your meds to contribute to your feelings of mild hypomania.
Thanks for your post. Let me know if you have any questions about anything that I've written.
Tomatheus
> hi,
> I'm on 3000mg daily vitamin c for my bipolar II and its doing wonders! great mood, high productivity... im living again... but i feel kinda hypomanic, more like a constant mild hypomania... i was wondering if there was any other thing i could add that could calm me down a little??
> bps
> ps. im gonna try magnesium with it soon
Posted by linkadge on July 28, 2006, at 22:05:34
In reply to Re: Type of vitamin C, posted by bipolarspectrum on July 28, 2006, at 9:40:05
I had it described that vitamin C has a stabilizing effect, and that magnesium is good to lower the mood a little.
I'd get some 50mg magnesium tablets, and just take them one at a time to see.
Linkadge
Posted by bipolarspectrum on July 29, 2006, at 4:16:44
In reply to Re: Type of vitamin C, posted by linkadge on July 28, 2006, at 22:05:34
Hi,
I just started folic acid at 400 mcgs and it has incredible stabillizing effects for me.. ive never been so calm before... but at the same time i think im taking too high a dose, as im gettin a nasty headache and feelin sedated, like im overly 'calm'... im gonna do down to 200 mcgs and see how it goes... but wow, i think folate is for real!
bps
Posted by dessbee on July 29, 2006, at 8:29:33
In reply to Re: Type of vitamin C, posted by bipolarspectrum on July 28, 2006, at 9:40:05
There is no such thing as regular vitamin c ;-)
Is it calcium ascorbate, sodium ascorbate or something else?
Posted by dessbee on July 29, 2006, at 8:56:53
In reply to TWO WORDS: FOLIC ACID!, posted by bipolarspectrum on July 29, 2006, at 4:16:44
I do not think you can evaluate any stabilizing effect on a single dose. Supplements have to be evaluated over a 2-3 months period.
Most B-vitamins have initial vitilizing effect.
Unfortunately they may aggravate compulsivity, especially folic acid.
Posted by bipolarspectrum on July 29, 2006, at 16:15:05
In reply to Re: TWO WORDS: FOLIC ACID! » bipolarspectrum, posted by dessbee on July 29, 2006, at 8:56:53
Hi D,
Great point... i think as a longtime sufferer i can get overly excited... but so far its been very stabilizing...
bps> I do not think you can evaluate any stabilizing effect on a single dose. Supplements have to be evaluated over a 2-3 months period.
>
> Most B-vitamins have initial vitilizing effect.
> Unfortunately they may aggravate compulsivity, especially folic acid.
>
>
Posted by linkadge on July 29, 2006, at 21:32:47
In reply to TWO WORDS: FOLIC ACID!, posted by bipolarspectrum on July 29, 2006, at 4:16:44
Yes, folic acid for me is a very imporant supplement. The effects of folic acid on cognition too, are pronounced. Folic acid deficinacy poses critical problems to hippocampal proliferation.
Some studies show that a nonresponse to certain antidepressants can turn into a response by adding folic acid.
Linkadge
Posted by linkadge on July 29, 2006, at 21:34:23
In reply to Re: TWO WORDS: FOLIC ACID!, posted by bipolarspectrum on July 29, 2006, at 16:15:05
The word I use for folic acid is: Sanitizing.
Linkadge
Posted by linkadge on July 29, 2006, at 21:37:23
In reply to Re: TWO WORDS: FOLIC ACID!, posted by bipolarspectrum on July 29, 2006, at 16:15:05
I think the below supplements should be considered for those with bipolar disorder.
Omega-3
Folic Acid
Vitamin C,
MagnesiumTaurine
Niacine,
Zinc,
THe effects of lithium and valproate are thought to be mediated by is GSK-3b inhibition, PKC inhibition, and BCL-2 upregulation. The same thing can be achieved withNiacin: GSK-3b inhibitor
Zinc, BCL-2 upregulation
O3/Taurine: PKC inhibition.Linkadge
Posted by janeB on August 9, 2006, at 14:13:29
In reply to Re: TWO WORDS: FOLIC ACID!, posted by linkadge on July 29, 2006, at 21:37:23
> I think the below supplements should be considered for those with bipolar disorder.
>
> Omega-3
> Folic Acid
> Vitamin C,
> Magnesium
>
> Taurine
> Niacine,
> Zinc,
>
>
> THe effects of lithium and valproate are thought to be mediated by is GSK-3b inhibition, PKC inhibition, and BCL-2 upregulation. The same thing can be achieved with
>
> Niacin: GSK-3b inhibitor
> Zinc, BCL-2 upregulation
> O3/Taurine: PKC inhibition.
>
> LinkadgeAre the above included in a multi vitamin? Are there any supplements that should NOT be considered for bipolar? What about a multi vitamin? What about B's?
What about someone with antidepressant induced cyclothymia? Does the same apply?
Jane
>
Posted by linkadge on August 9, 2006, at 18:18:48
In reply to Re: TWO WORDS: FOLIC ACID! » linkadge, posted by janeB on August 9, 2006, at 14:13:29
I think that a multi containing no more than 100% of the RDI (or less) is probably ok for most disorders.
Its when the does are in a much higher magnitide that they can become theraputic.
I know for instance, that copper tends to be high in bipolars and paranoid individuals (a bit of a generalization), so it might be advantagious to experiment a little with individual supplements.
I know its a pain, but it *may* yeild better results.
A hair analysis might be of some use to start.
Though, somebody else might be able to comment on the accuracy of them.
Linkadge
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