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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Mistermindmasta on June 27, 2006, at 22:03:23
Sorry to post a new thread, since this is sort of a reply to an old thread, but I feel it's important to re-engage the vitamin D discussion. Vitamin D may be VERY VERY important for some people.
So anyway, someone wrote, regarding Larry Hoover saying that the optimal level of intake of D is 4,000 IU vitamin / day:
"I disagree. Your recommendations might actually kill someone. Vitamin D is the most toxic vitamin known to man. 4000 IU of Vitamin D will cause hypercalcemia and calcification of blood vessels.
You seem too think the more the better. It is quite the opposite. Larry, start staking 4000 IU today and I promise you will not be a part of this forum anymore!"
I just wanted to say that I sort of am a little bit of a vitamin D fanatic/obsessive, keeping up with ALL the latest studies and info. Vitamin D WILL NOT cause hypercalcemia at 4,000 IU / day. Vitamin D WILL cause hypercalcemia at that dose if you have what is known as "vitamin D hypersensitivity syndrome". In fact, there are no known cases of any healthy person having vitamin D toxicity from anything less than 10,000 IU / day!!!! Seriously! That's 20 times the RDA!!!!! MOST people indeed do NOT have the vitamin D receptor polymorphism that causes this vitamin D hypersensitivity phenomenon... ESPECIALLY people who have immune system disorders with a tendency toward autoimmune problems or people with psychiatric illness.
I've been taking 5,000 IU / day for the past 3 months with zero side effects. Zero. I feel fine. But anyway, that's only me. On to the real evidence. Go ahead and check out www.direct-ms.org. It's a multiple sclerosis website, but is nontheless useful in obtaining the highest quality, most recent vitamin d recommendations and information. I invite you to listen to the presentations regarding vitamin D at http://www.direct-ms.org/presentations.html. You will then find that there are zero biochemical abnormalities from continuous, long term dosing of 4,000 IU vitamin D per day, aside from achieving vitamin D status that closely parellels what humans living 10,000 years ago would have achieved. THIS IS IMPORTANT STUFF TO KNOW!!! The world's most knowledgable vitamin D experts state that, at the very least, everyone should be taking 1,000 - 2,000 IU / day, no question about it. Summer or winter, it doesn't matter. But, since 4,000 IU in fact is perfectly safe, why not do more? Why NOT use 4,000 IU per day when it might be critical for people with immune system problems or psychiatric illness?
Vitamin D is involved in regulation of development of T cells, it's involved in the synthesis of critical antimicrobial peptides, and there are numerous vitamin D receptors that play important role in neuromodulation. If you choose not to check out the www.direct-ms.org info, then go to www.pubmed.org. Type "vitamin D" and just check out the latest research in the past year. It's VERY important stuff and very interesting. So interesting in fact, that this www.direct-ms.org website believes that adequate vitamin D throughout one's life can actually prevent autoimmune diseases like rheumatoid arthritis and MS through appropriate regulation of T-cells. For someone with Crohn's disease like myself, there is no doubt in my mind that 2,000 - 4,000 IU of vitamin D per day is optimal for me.
Anyway, that's my lecture, haha. I really want everyone who reads this to check out the 2 websites I recommended and see what you find. It's good stuff. 4,000 IU is safe.
Posted by ElaineM on June 27, 2006, at 22:30:22
In reply to Vitamin D - 4,000 IU / day, posted by Mistermindmasta on June 27, 2006, at 22:03:23
Thanks for the websites. I take 2000IU a day. My alternative med doc wants me to go even higher. I am always concerned about mega-dosing, but I guess you get to the point where you'll give anything a shot. And she is always doing urinanalysis to watch for levels of something(not sure what she said exactly). She takes much higher doses herself, and lectures all over about the effects of high doses of vit D (she's big on cal/mag too) on alleviating symptoms of chronic pain. I'd never heard of it before but have become more interested as my desperation and doses increase. I'll definately read that info.
EL
Posted by dessbee on July 15, 2006, at 20:00:01
In reply to Re: Vitamin D - 4,000 IU / day, posted by ElaineM on June 27, 2006, at 22:30:22
SJW induce liver metabolising enzymes (e.g. cytochrome P450s), which leads to altered drug concentration and clearance.
http://www.innovationmagazine.com/innovation/volumes/v6n2/coverstory3.shtml
I do not think it is a major concern for you if you only take codeine, but make sure to ask your doctor. SJW is a safe supplement for most people.
4,000 IU! I still claim that sun exposure is the safest way to increase vitamine D. Human beings feel better if they get a daily dose of sun exposure. Sunexposure will give you much higher vitamin D concentrations without any health risks unless you get burned in the sun.
Osteoporosis is also improved by exercise!
Another factor important to cure osteoprosis is vitamin K, especially vitamin K2.
http://www.spineuniverse.com/displayarticle.php/article1081.html
http://altmedicine.about.com/cs/womenshealth/a/Osteoprevent.htm
http://www.findarticles.com/p/articles/mi_m0FDN/is_1_10/ai_n13557316
Melatonin is not really anything I recommend since it will only help you falling asleep. The effect of 2mg will wear off quickly and therefore will not be able to improve deep sleep, at least not in my oppinion.
If SJW is not an option for you you could try Seroctin at bedtime. It increases the release of serotonin/melatonin.
Cortisol has a degenerative effect on any tissue including bone tissue. Another supplement that may lower cortisol levels is vitamin C, which is also good for building bone tissue.
I still do not understand your pain disorder.
This is the end of the thread.
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