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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by Spriggy on February 4, 2005, at 17:19:11
I've posted on the regular babble but you really seem to know your "stuff." (and anyone else who has some advice)
Brief history: am pretty reactive to certain meds. I was given Compazine (and Phenergen) a few times for a stomach bug and both wigged me out. Made me EXTREMELY uncomfortable, restless, and felt very bizarre on both.
* Tried melatonin for about 2 weeks and had the same response to melatonin (3 mg's). That really strange "head" feeling like my mind was sooo restless and made me very uncomfortable.
I've had a few panic attacks in my life- only one was not triggered by the medicine. My doctor convinced me to try Wellbutrin XL (because my father is dying and she was concerned it would cause my anxiety to sky rocket).
I can't for CERTAIN it was the Wellbutrin but on day 2, I went into all I know to call a "manic" and very distressed, agitated state for almost 5 days. I could NOT sleep, did not eat, could not stop my mind from racing, and felt generally in the worst state of anxiety in my life.
So I quit the Wellbutrin.
Dr. then says, " let's try Lexapro."
2 weeks into Lexapro a very similar reaction (only I could sleep). I felt very agitated in my head, could not "rest, a very uncomfortable in my own skin feeling. I then would have moments of BRIEF euphoria followed by the deepest, darkest, depression in my life. I mean utter despair. It would swing back and forth several times throughout the day.. from euphoric, to very restless, to extremely depresssed.
Went to the pdoc becuase my dr. suspected "bipolar", but pdoc thought I was just having a reaction the AD's.
So I am on day 5 without any Lexapro ( I weaned off slowly) and am still feeling kind of bizarre.
Any ideas what I could take to help this?
Would St. John's Wort be helpful?
If I am sensitive to having my seratonin messed with, would ST. JOhn's wort be safe or not?
I am just thoroughly confused and don't want to be put back on more weird medicine from the doctor that will make me worse.
Posted by Larry Hoover on February 14, 2005, at 11:51:35
In reply to Larry? Oh smart one.., posted by Spriggy on February 4, 2005, at 17:19:11
> Any ideas what I could take to help this?
Rather than what to take, the issue may well be "how much" to take. With your sensitivity to meds, you may simply require less drug to have a typical effect. It's seldom considered by doctors, but the range of the dose to serum concentration can be substantial, in different people. Also, the range of serum concentration to drug response is variable. It may sound absurd to some doctors, but you might get by on as little as 10% of the dose that others need.
> Would St. John's Wort be helpful?
>
> If I am sensitive to having my seratonin messed with, would ST. JOhn's wort be safe or not?SJW is probably the gentlest antidepressant of proven efficacy I've ever come across. In other words, with your sensitivity, it may well make sense to try it.
> I am just thoroughly confused and don't want to be put back on more weird medicine from the doctor that will make me worse.The other option is just don't take as much of the meds as you're given. Be the "gatekeeper" for your body. Control what you swallow. Ya know?
Lar
This is the end of the thread.
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