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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by Lamdage22 on May 8, 2018, at 1:06:20
I have real bad congestion at nighttime when i take the 400mg Seroquel. In the morning i am not congested. Is Seroquel more likely to cause allergy than Zyprexa?
I wonder what this is.
Posted by SLS on May 8, 2018, at 5:28:35
In reply to Am i allergic to Seroquel or another med?, posted by Lamdage22 on May 8, 2018, at 1:06:20
> I have real bad congestion at nighttime when i take the 400mg Seroquel. In the morning i am not congested. Is Seroquel more likely to cause allergy than Zyprexa?
>
> I wonder what this is.Your experience with Seroquel is not uncommon - nasal congestion. My first guess is that the congestion is due to NE alpha 1 receptor antagonism. You might want to experiment with lower dosages taken at night. You really are on high dosages of antipsychotics. Have you ever thought to replace Seroquel with Remeron? This should take care of insomnia. You can then replace Zyprexa with perphenazine for anxiety and delusions if these things are problems.
- Scott
Posted by Lamdage22 on May 8, 2018, at 7:04:56
In reply to Re: Am i allergic to Seroquel or another med? » Lamdage22, posted by SLS on May 8, 2018, at 5:28:35
Hi Scott, thanks for your insight. I will call my doctor in an hour. I think he is leaning more toward eliminating Seroquel (not Zyprexa), anyway.
I will let the doctor decide i think
Posted by sigismund on May 8, 2018, at 10:08:34
In reply to Re: Am i allergic to Seroquel or another med?, posted by Lamdage22 on May 8, 2018, at 7:04:56
My experience has been that a lot of meds/dugs over time can contribute to a reactive inflammatory state. Allergies being typical. High IgE for example.
Posted by SLS on May 8, 2018, at 11:43:26
In reply to Re: Am i allergic to Seroquel or another med?, posted by sigismund on May 8, 2018, at 10:08:34
> My experience has been that a lot of meds/dugs over time can contribute to a reactive inflammatory state. Allergies being typical. High IgE for example.
Which drugs affected you the most? How did you determine your inflammatory state?
Thanks.
- Scott
Posted by Lamdage22 on May 8, 2018, at 12:15:43
In reply to Re: Am i allergic to Seroquel or another med? » sigismund, posted by SLS on May 8, 2018, at 11:43:26
why would perphenazine be better than Seroquel or Zyprexa?
If we are talking OCD, which one of the 3 is best in regard to OCD?
Posted by sigismund on May 8, 2018, at 13:37:26
In reply to Re: Am i allergic to Seroquel or another med? » sigismund, posted by SLS on May 8, 2018, at 11:43:26
>Which drugs affected you the most? How did you determine your inflammatory state?
Well, that's a good question but I don't really know. Benzos perhaps?
I do mean long term, over decades.
Of course any drug will have more immediate effects one way or the other.
Posted by SLS on May 8, 2018, at 14:44:07
In reply to Re: Am i allergic to Seroquel or another med?, posted by Lamdage22 on May 8, 2018, at 12:15:43
> why would perphenazine be better than Seroquel or Zyprexa?
Perphenazine does not produce weight gain or diabetes. It is good for anxiety and delusions. I would call it a medium potency antipsychotic. Another option would be to cross over from Seroquel to Saphris. Saphris does not produce weight gain and is supposedly good for both depression and delusions. I don't know about anxiety per se, but it does block 5-HT2 and other serotonin receptors. This might confer some anxiolytic action.
> If we are talking OCD, which one of the 3 is best in regard to OCD?
Regarding OCD, Zyprexa has been reported to be helpful as an anti-obsessional. I could find nothing that would lead me to believe that perphenazine is as helpful.
Can you describe what you experience as OCD?
Is there any way to get you off of Effexor and on Luvox? You could bring the Luvox on board first and then try cutting down the Effexor more rapidly.
- Scott
Posted by Lamdage22 on May 9, 2018, at 10:50:02
In reply to Re: Am i allergic to Seroquel or another med? » Lamdage22, posted by SLS on May 8, 2018, at 14:44:07
> > why would perphenazine be better than Seroquel or Zyprexa?
>
> Perphenazine does not produce weight gain or diabetes. It is good for anxiety and delusions. I would call it a medium potency antipsychotic. Another option would be to cross over from Seroquel to Saphris. Saphris does not produce weight gain and is supposedly good for both depression and delusions. I don't know about anxiety per se, but it does block 5-HT2 and other serotonin receptors. This might confer some anxiolytic action.
>
> > If we are talking OCD, which one of the 3 is best in regard to OCD?
>
> Regarding OCD, Zyprexa has been reported to be helpful as an anti-obsessional. I could find nothing that would lead me to believe that perphenazine is as helpful.
>
> Can you describe what you experience as OCD?
>
> Is there any way to get you off of Effexor and on Luvox? You could bring the Luvox on board first and then try cutting down the Effexor more rapidly.
>
>
> - ScottHey Scott, i did try Luvox and it slows the metabolism of all other drugs. I was very sedated.
My Dr does not want to do quick changes since i have been relatively stable for several years. We dont want to tear that down. Since i take less Seroquel at night because of the nasal congestion from it the Dr prescribed Prothipendyl so i will still be able to sleep.I need the Seroquel to sleep you know? It is more sedating than Zyprexa at these megadoses.
I will let you guys know how i do on Prothipendyl.
Posted by Lamdage22 on May 9, 2018, at 10:56:22
In reply to Re: Am i allergic to Seroquel or another med?, posted by Lamdage22 on May 9, 2018, at 10:50:02
How high is the TD/movement disorder risk with high dose Perphenazine? More than 1 in 10? 1 in 10? 1 in 100? 1 in 1000? How does it compare to Seroquel and Zyprexa?
Thanks
Posted by SLS on May 9, 2018, at 11:35:58
In reply to Re: Am i allergic to Seroquel or another med?, posted by Lamdage22 on May 9, 2018, at 10:50:02
> I will let you guys know how i do on Prothipendyl.
Interesting choice. It sounds like you have a good doctor. Good luck with it.
- Scott
Posted by Lamdage22 on May 10, 2018, at 12:32:03
In reply to Re: Am i allergic to Seroquel or another med? » Lamdage22, posted by SLS on May 9, 2018, at 11:35:58
It seems to do the job. I took less Seroquel, i could breathe through the nose and i could sleep.
Posted by Lamdage22 on May 11, 2018, at 7:35:27
In reply to Prothipendyl seems to help my sleep, posted by Lamdage22 on May 10, 2018, at 12:32:03
I got inflamed eyelids and no idea where it is coming from. Can it be tested if im allergic to something i take?
Posted by Lamdage22 on May 19, 2018, at 8:34:41
In reply to How likely is it to be allergic to a med?, posted by Lamdage22 on May 11, 2018, at 7:35:27
Ok i reckon its not very likely
Posted by Lamdage22 on May 20, 2018, at 8:02:34
In reply to Re: How likely is it to be allergic to a med?, posted by Lamdage22 on May 19, 2018, at 8:34:41
My pdoc went from 1000mg to 900 mg with the Seroquel (200mg instead of 300mg Seroquel prolong in the morning).
No more congestion. Thanks for the responses.
This is the end of the thread.
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