Psycho-Babble Medication Thread 1088791

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Naltrexone side effects?

Posted by zonked on May 8, 2016, at 11:07:48

Hey guys,

I may be going to Vegas in a few weeks to visit a friend - and I was wondering, since Naltrexone is an opiod antagonist, if anyone using this has had depression or anxiety as a side effect.

It's in case I goof and actually drink.

I don't expect to.

-z

 

Re: Naltrexone side effects? » zonked

Posted by J Kelly on May 8, 2016, at 15:26:32

In reply to Naltrexone side effects?, posted by zonked on May 8, 2016, at 11:07:48

> Hey guys,
>
> I may be going to Vegas in a few weeks to visit a friend - and I was wondering, since Naltrexone is an opiod antagonist, if anyone using this has had depression or anxiety as a side effect.
>
> It's in case I goof and actually drink.
>
> I don't expect to.
>
> -z

Hi Z,

I have no personal experience with this drug but came across this:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325065/

Jade

 

Re: Naltrexone side effects?

Posted by baseball55 on May 8, 2016, at 19:16:02

In reply to Naltrexone side effects?, posted by zonked on May 8, 2016, at 11:07:48

Naltrexone never impacted my response to alcohol at all. It's an opioid antagonist. If you're taking it after being on opioids, depression is a common side effect, until your endorphins come back. My p-doc prescribed vigorous exercise and very low doses for a few weeks to prevent depression. I don't understand why naltrexone is used for alcohol dependence I drank on naltrexone without any effect at all.

> Hey guys,
>
> I may be going to Vegas in a few weeks to visit a friend - and I was wondering, since Naltrexone is an opiod antagonist, if anyone using this has had depression or anxiety as a side effect.
>
> It's in case I goof and actually drink.
>
> I don't expect to.
>
> -z

 

Re: Naltrexone side effects? » baseball55

Posted by Horse on May 9, 2016, at 19:30:12

In reply to Re: Naltrexone side effects?, posted by baseball55 on May 8, 2016, at 19:16:02

I've suspected that naltrexone used for alcohol is bad/stupid science on the part ofsome alcohol rehab establishments.

 

Re: Naltrexone side effects?

Posted by SLS on May 20, 2016, at 9:47:34

In reply to Re: Naltrexone side effects? » baseball55, posted by Horse on May 9, 2016, at 19:30:12

> I've suspected that naltrexone used for alcohol is bad/stupid science on the part ofsome alcohol rehab establishments.

I was thinking that substituting naloxone with naltrexone would retain the effects that discourage heroin use. Suboxone sometimes causes sedation and excessive sleep. Perhaps tramadol could substitute for buprenorphine.

The advantages to using (tramadol + naltrexone) in place of (buprenorphine + naloxone) - if it works - include the convenience of dosing orally instead of sublingually. It can also be prescribed by a family physician, and tweaked more easily by being able to adjust the dosages of each drug separately.

I have no idea if this idea is workable, but a friend of mine is not doing well with suboxone because of its sedating and soporific side effects. However, he has not relapsed into heroin use.

Any thoughts?


- Scott

 

Re: Naltrexone side effects? » SLS

Posted by Horse on May 20, 2016, at 17:55:06

In reply to Re: Naltrexone side effects?, posted by SLS on May 20, 2016, at 9:47:34

> > I've suspected that naltrexone used for alcohol is bad/stupid science on the part of some alcohol rehab establishments.
>
> I was thinking that substituting naloxone with naltrexone would retain the effects that discourage heroin use. Suboxone sometimes causes sedation and excessive sleep. Perhaps tramadol could substitute for buprenorphine.
>
> The advantages to using (tramadol + naltrexone) in place of (buprenorphine + naloxone) - if it works - include the convenience of dosing orally instead of sublingually. It can also be prescribed by a family physician, and tweaked more easily by being able to adjust the dosages of each drug separately.
>
> I have no idea if this idea is workable, but a friend of mine is not doing well with suboxone because of its sedating and soporific side effects. However, he has not relapsed into heroin use.
>
> Any thoughts?
>
>
> - Scott


I meant for alcohol abuse treatment. Naltrexone treatment wouldn't be a deterrent because alcohol works on gaba? Or I may be misunderstanding both the thread and the subject :)


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